Sundaresan N, DiGiacinto G V
Med Clin North Am. 1987 Mar;71(2):329-48. doi: 10.1016/s0025-7125(16)30874-4.
Patients with cancer pain often present with specific clinical syndromes that allow specific anti-tumor approaches. If these approaches are not feasible, neurosurgical procedures for pain relief should be considered. The major advantage of neurosurgical procedures is freedom from the excessive side effects of narcotic therapy. The most durable pain procedure is cordotomy, while intraspinal narcotics offer a rational treatment alternative in selected patients. Spinal and plexopathy syndromes that are amenable to more specific anti-tumor therapy should be looked for, since newer surgical approaches offer the prospect of both pain relief and tumor control.
癌症疼痛患者常表现出特定的临床综合征，从而可采用特定的抗肿瘤方法。如果这些方法不可行，则应考虑采用神经外科手术来缓解疼痛。神经外科手术的主要优点是可避免麻醉治疗的过度副作用。最持久的止痛手术是脊髓前侧柱切断术，而脊髓内注射麻醉剂为部分患者提供了合理的治疗选择。对于适合更具针对性抗肿瘤治疗的脊柱和神经丛病变综合征，应予以查找，因为新的手术方法有望实现止痛和控制肿瘤的双重效果。
