Trivedi Dhiraj J, Kulkarni Shrirang P, Mudaraddi Rakesh
Department of Biochemistry, SDM College of Medical Sciences and Hospital, Dharwad, Karnataka India.
Indian J Clin Biochem. 2017 Jul;32(3):367-369. doi: 10.1007/s12291-016-0607-4. Epub 2016 Aug 25.
Myoglobin is dark red colour heme containing protein, stored in muscle. Change in permeability of myolemma causes myoglobin leak in plasma, which is cleared by kidney swiftly. Differentiating myoglobinuria from hemoglobinuria is important. Clinicians concern over myoglobinuria is to protect the patient from acute renal disease. We present a case of primary myoglobinuria, its clinical symptoms, diagnosis and treatment.
肌红蛋白是一种深红色的含血红素蛋白,储存于肌肉中。肌细胞膜通透性改变会导致肌红蛋白漏入血浆,而肾脏会迅速将其清除。区分肌红蛋白尿和血红蛋白尿很重要。临床医生关注肌红蛋白尿是为了保护患者免受急性肾脏疾病的侵害。我们报告一例原发性肌红蛋白尿病例,及其临床症状、诊断和治疗。