Zeb Shah, Ashraf Tariq, Hashim Muhammad, Rizvi Syed Nadeem Hassan
Shah Zeb, MRCP, FCPS. Department of Interventional Cardiology, National Institute of Cardiovascular Disease, Karachi, Pakistan.
Tariq Ashraf, FCPS, FACC. Department of Interventional Cardiology, National Institute of Cardiovascular Disease, Karachi, Pakistan.
Pak J Med Sci. 2017 May-Jun;33(3):529-533. doi: 10.12669/pjms.333.12565.
To know the regression of right ventricular pressure after successful percutaneous transluminalmitral commissurotomy (PTMC) in patients with severe isolated mitral stenosis.
This descriptive study was performed in inpatient and outpatient department of National Institute of Cardiovascular Disease from 1 February 2016 to 31 August 2016. Echocardiography of all patients with successful PTMC were recorded 24 hours and 06 months following PTMC to see for Regression of right ventricular pressure along with other baseline echocardiographic parameters.
A total of 99 patients with severe isolated mitral stenosis who had undergone successful PTMC were studied. Females were 65(65.7%) and males 34(34.3%). Mean age was 27.44±6.26 years. TTE performed before and after PTMC showed significant difference in mean mitral valve area (0.89cm ±0.089cm2 vs. 1.68±0.128 cm2, p valve <0.001) and mean left atrial diameter (4.66± .82cm vs. 4.46± 0.65cm). Mean mitral valve gradient pre PTMC was significantly higher (16.38±2.51 mm of Hg) than that of post PTMC 24 hours (4.75±1.31 mm of Hg) and Post PTMC 06 months (5.22±1.21 mm of Hg), p valve <0.001. Mean right ventricular systolic pressure (RVSP) pre PTMC was significantly higher 62.3±10.91 mm of Hg than that of post PTMC 24 hour's 57.51±9.67 mm of Hg and post PTMC 06 moths 46.49±7.8mm of Hg, p value 0.001. Mean LVEF 50.14± 5.82.
There was a significant regression of right ventricular pressure following successful PTMC in mid-term (06 months) follow up of severe isolated mitral stenosis patients.
了解重度单纯二尖瓣狭窄患者经皮二尖瓣球囊成形术(PTMC)成功后右心室压力的下降情况。
本描述性研究于2016年2月1日至2016年8月31日在国家心血管病研究所的门诊和住院部进行。对所有PTMC成功的患者在PTMC后24小时和6个月进行超声心动图检查,观察右心室压力的下降情况以及其他基线超声心动图参数。
共研究了99例重度单纯二尖瓣狭窄且PTMC成功的患者。女性65例(65.7%),男性34例(34.3%)。平均年龄为27.44±6.26岁。PTMC前后进行的经胸超声心动图(TTE)显示,平均二尖瓣面积(0.89cm²±0.089cm² 对 1.68±0.128cm²,p值<0.001)和平均左心房直径(4.66±0.82cm对4.46±0.65cm)有显著差异。PTMC前的平均二尖瓣压差显著高于PTMC后24小时(4.75±1.31mmHg)和PTMC后6个月(5.22±1.21mmHg),p值<0.001。PTMC前的平均右心室收缩压(RVSP)显著高于PTMC后24小时的57.51±9.67mmHg和PTMC后6个月的46.49±7.8mmHg,p值0.001。平均左心室射血分数(LVEF)为50.14±5.82。
在重度单纯二尖瓣狭窄患者的中期(6个月)随访中,PTMC成功后右心室压力有显著下降。