Haider Jamila, Lufullah Ghosia, Nazli Rubina, Akhtar Tasleem, Shah Asma
Jamila Haider, BS, PhD Scholar. Lecturer, Centre for Biotechnology & Microbiology, University of Swat, Swat, Pakistan.
Prof. Dr. Ghosia Lutfullah, M.Phil, Ph.D. Director, Centre of Biotechnology & Microbiology, University of Peshawar, Peshawar, Pakistan.
Pak J Med Sci. 2017 May-Jun;33(3):615-620. doi: 10.12669/pjms.333.12260.
To screen out adult patients for HBV and HCV infections visiting Khyber College of Dentistry Peshawar (KCD) for different dental treatments and to identify the associated risk factors.
This cross-sectional study was conducted at Khyber College of Dentistry, Peshawar in the year 2013. A total of 1540 patients >15 years, visiting KCD for seeking different dental treatments were screened for hepatitis B & C. Informed consent was taken before blood collection and filling of a structured questionnaire. Blood samples were tested against HBsAg and anti HCV by using ICT that were further confirmed by ELISA. The data was analyzed using Epi info version 6.
A total of 1540 patients were screened during the study. Among these 36.4%(561) were males and 63.6%(979) were females. Overall prevalence of HBV and HCV was 5.12%(79). On screening, 2.14%(33) were found to be HBs Ag positive of which 2.5%(14) were males and 1.9%(19) were females. HCV was found positive in 2.98%(46) individuals having male to female ratio of 1.6% and 3.8%. Frequency of HBsAg was high in age group 56-65 year and HCV in 36-45 year group. Previous history of IV/IM injections, spouse patient of hepatitis, blood transfusion, surgical operation were found significant risk factors in the transmission of both hepatitis B and C, while previous history of dental treatment and sharing of clippers were significant risk factor in spreading hepatitis C infection only.
Overall prevalence of HCV was higher than HBV. Previous history of injections, spouse patient of hepatitis, blood transfusion, surgical operation were found significant risk factors in the transmission of both hepatitis B and C.
筛查前往白沙瓦开伯尔牙科学院（KCD）接受不同牙科治疗的成年患者是否感染乙肝病毒（HBV）和丙肝病毒（HCV），并确定相关危险因素。
本横断面研究于2013年在白沙瓦开伯尔牙科学院开展。共对1540名年龄大于15岁、前往KCD寻求不同牙科治疗的患者进行了乙肝和丙肝筛查。在采集血液和填写结构化问卷前获取了知情同意书。采用免疫层析法（ICT）检测血液样本中的乙肝表面抗原（HBsAg）和抗HCV，并用酶联免疫吸附测定法（ELISA）进一步确认。使用Epi info 6版本对数据进行分析。
研究期间共筛查了1540名患者。其中，男性占36.4%（561人），女性占63.6%（979人）。HBV和HCV的总体患病率为5.12%（79人）。筛查发现，2.14%（33人）为HBsAg阳性，其中男性占2.5%（14人），女性占1.9%（19人）。HCV在2.98%（46人）的个体中呈阳性，男女比例分别为1.6%和3.8%。HBsAg在56 - 65岁年龄组中的检出频率较高，HCV在36 - 45岁年龄组中的检出频率较高。静脉内/肌内注射史、配偶为肝炎患者、输血史、外科手术史被发现是乙肝和丙肝传播的重要危险因素，而牙科治疗史和共用理发推子则是仅传播丙肝感染的重要危险因素。
HCV的总体患病率高于HBV。注射史、配偶为肝炎患者、输血史、外科手术史被发现是乙肝和丙肝传播的重要危险因素。
