Galarza M, Giménez A, Amigó J M, Schuhmann M, Gazzeri R, Thomale U, McAllister J P
Regional Service of Neurosurgery, University of Murcia, Murcia, Spain.
Operations Research Center, University Miguel Hernández de Elche, Alacant, Spain.
Childs Nerv Syst. 2018 Feb;34(2):267-276. doi: 10.1007/s00381-017-3565-0. Epub 2017 Aug 15.
The flow pattern of the cerebrospinal fluid is probably the most important factor related to obstruction of ventricular catheters during the normal treatment of hydrocephalus. To better comprehend the flow pattern, we have carried out a parametric study via numerical models of ventricular catheters. In previous studies, the flow was studied under steady and, recently, in pulsatile boundary conditions by means of computational fluid dynamics (CFD) in three-dimensional catheter models.
This study aimed to bring in prototype models of catheter CFD flow solutions as well to introduce the theory behind parametric development of ventricular catheters.
A preceding study allowed deriving basic principles which lead to designs with improved flow patterns of ventricular catheters. The parameters chosen were the number of drainage segments, the distances between them, the number and diameter of the holes on each segment, as well as their relative angular position.
CFD results of previously unreleased models of ventricular catheter flow solutions are presented in this study. Parametric development guided new designs with better flow distribution while lowering the shear stress of the catheters holes. High-resolution 3D printed catheter solutions of three models and basic benchmark testing are introduced as well.
The next generation of catheter with homogeneous flow patterns based on parametric designs may represent a step forward for the treatment of hydrocephalus, by possibly broadening their lifespan.
在脑积水的常规治疗过程中,脑脊液的流动模式可能是与脑室导管阻塞相关的最重要因素。为了更好地理解流动模式,我们通过脑室导管的数值模型进行了参数研究。在先前的研究中,通过三维导管模型中的计算流体动力学(CFD)在稳定边界条件下以及最近在脉动边界条件下研究了流动情况。
本研究旨在引入导管CFD流动解决方案的原型模型,并介绍脑室导管参数化开发背后的理论。
先前的一项研究得出了一些基本原则,这些原则可用于设计具有改善的脑室导管流动模式的产品。所选择的参数包括引流段的数量、它们之间的距离、每个段上孔的数量和直径,以及它们的相对角位置。
本研究展示了先前未发布的脑室导管流动解决方案模型的CFD结果。参数化开发指导了新的设计,这些设计具有更好的流动分布,同时降低了导管孔处的剪切应力。还介绍了三种模型的高分辨率3D打印导管解决方案以及基本的基准测试。
基于参数化设计的具有均匀流动模式的下一代导管可能代表了脑积水治疗的一个进步,因为这可能会延长它们的使用寿命。