Department of Biomedical Engineering, University of Wisconsin-Madison College of Engineering, Madison, Wisconsin; and.
Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin.
Physiology (Bethesda). 2017 Sep;32(5):346-356. doi: 10.1152/physiol.00040.2016.
Accurate and comprehensive evaluation of right ventricular (RV)-pulmonary vascular (PV) interactions is critical to the assessment of cardiopulmonary function, dysfunction, and failure. Here, we review methods of quantifying RV-PV interactions and experimental results from clinical trials as well as large- and small-animal models based on pressure-volume analysis. We conclude by outlining critical gaps in knowledge that should drive future studies.
准确全面地评估右心室(RV)-肺血管(PV)相互作用对于评估心肺功能、功能障碍和衰竭至关重要。在这里,我们回顾了基于压力-容积分析的定量 RV-PV 相互作用的方法和来自临床试验以及大、小动物模型的实验结果。最后,我们概述了应该推动未来研究的知识空白。