Hattahara Kodai, Hamada Akihiro, Oyama Rie, Masui Kimihiko, Shichiri Yasumasa
The Department of Urology, Otsu Municipal Hospital.
Hinyokika Kiyo. 2017 Jul;63(7):275-278. doi: 10.14989/ActaUrolJap_63_7_275.
A man aged 83 years under treatment with enzalutamide for castration-resistant prostate cancer presented with general malaise and exertional dyspnea. The underlying cause could not be identified by further investigations. On the 5th hospital day, he died due to a sudden exacerbation of dyspnea. The results of an autopsy indicated tumor emboli and stenosis of small pulmonary arteries with the fibrocellular intimal thickening, and therefore our final diagnosis was pulmonary tumor thrombotic microangiopathy.
一名83岁正在接受恩杂鲁胺治疗的去势抵抗性前列腺癌患者，出现全身不适和劳力性呼吸困难。进一步检查未能明确潜在病因。住院第5天，他因呼吸困难突然加重而死亡。尸检结果显示有肿瘤栓子以及小肺动脉狭窄伴纤维细胞内膜增厚，因此我们的最终诊断是肺肿瘤血栓性微血管病。
