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美国乳腺癌患者的生存率存在差异吗?一项来自六个随机选取州的研究。

Does Survival Vary for Breast Cancer Patients in the United States? A Study from Six Randomly Selected States.

作者信息

Khan Hafiz M R, Gittner Lisaann S, Perisetti Abhilash, Saxena Anshul, Rafiq Aamrin, Gabbidon Kemesha, Mende Sarah, Lyuksyutova Maria

机构信息

Department of Public Health, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.

Department of Political Science, Texas Tech University, Lubbock, TX 70409, USA.

出版信息

J Environ Public Health. 2017;2017:6950579. doi: 10.1155/2017/6950579. Epub 2017 Jul 26.

Abstract

BACKGROUND

Breast cancer is the most common cancer in women. Disparities in some characteristics of breast cancer patients and their survival data for six randomly selected states in the US were examined.

MATERIALS AND METHODS

A probability random sampling method was used to select the records of 2,000 patients from each of six randomly selected states. Demographic and disease characteristics were extracted from the Surveillance Epidemiology and End Results (SEER) database. To evaluate relationships between variables, we employed a Cox Proportional Regression to compare survival times in the different states.

RESULTS

Iowa had the highest mean age of diagnosis at 64.14 years (SE = 0.324) and Georgia had the lowest at 57.97 years (SE = 0.313). New Mexico had the longest mean survival time of 189.09 months (SE = 20.414) and Hawaii the shortest at 119.01 (SE = 5.394) months, a 70.08-month difference (5.84 years). Analysis of stage of diagnosis showed that the highest survival times for Whites and American Indians/Alaska Natives were for stage I cancers. The highest survival times for Blacks varied. Stage IV cancer consistently showed the lowest survival times.

CONCLUSIONS

Differences in breast cancer characteristics across states highlight the need to understand differences between the states that result in variances in breast cancer survival.

摘要

背景

乳腺癌是女性中最常见的癌症。对美国随机选取的六个州的乳腺癌患者的某些特征及其生存数据的差异进行了研究。

材料与方法

采用概率随机抽样方法,从随机选取的六个州中各选取2000例患者的记录。从监测、流行病学和最终结果(SEER)数据库中提取人口统计学和疾病特征。为了评估变量之间的关系,我们采用Cox比例回归来比较不同州的生存时间。

结果

爱荷华州的平均诊断年龄最高,为64.14岁(标准误=0.324),佐治亚州最低,为57.97岁(标准误=0.313)。新墨西哥州的平均生存时间最长,为189.09个月(标准误=20.414),夏威夷州最短,为119.01个月(标准误=5.394),相差70.08个月(5.84年)。对诊断阶段的分析表明,白人和美洲印第安人/阿拉斯加原住民在I期癌症时的生存时间最长。黑人的最长生存时间各不相同。IV期癌症的生存时间一直最低。

结论

各州乳腺癌特征的差异凸显了了解导致乳腺癌生存差异的各州之间差异的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab53/5549473/19af6b30bce5/JEPH2017-6950579.001.jpg

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