Sorkin Nir, Kaiserman Igor, Domniz Yuval, Sela Tzahi, Munzer Gur, Varssano David
Department of Ophthalmology, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Care Laser Inc., Tel Aviv, Israel.
J Ophthalmol. 2017;2017:2434830. doi: 10.1155/2017/2434830. Epub 2017 Jul 26.
To analyze the risk factors associated with a series of ectasia cases following photorefractive keratectomy (PRK) and all published cases.
In a retrospective study on post-PRK ectasia patients, 9 eyes of 7 patients were included, in addition to 20 eyes of 13 patients from the literature. Risk of post-PRK ectasia was calculated using the ectasia risk score system (ERSS) for laser in situ keratomileusis (LASIK) patients. The percent tissue altered (PTA) was also evaluated.
ERSS scoring of zero for age, RSB, and spherical equivalent was found in 66%, 86%, and 86% of the eyes, respectively. Pachymetry risk score was 2 in 60% of the eyes and 3 or 4 in 16% of the eyes. Topography risk score was 3 in 41% of the eyes and 4 in 21% of the eyes. Cumulative ectasia risk score was ≥4 (high risk) in 77% of the eyes and ≥3 (medium and high risk) in 86% of the eyes. Average PTA was 23.2 ± 7.0%. All eyes but one had a PTA < 40%.
Preoperative corneal topographic abnormalities and thin corneas may be significant risk factors for developing ectasia following PRK. Post-LASIK ectasia risk scoring also has relevance in the risk for developing post-PRK ectasia.
分析准分子激光角膜切削术(PRK)后一系列角膜扩张病例以及所有已发表病例的相关危险因素。
在一项针对PRK术后角膜扩张患者的回顾性研究中,纳入了7例患者的9只眼,此外还纳入了文献中13例患者的20只眼。使用针对准分子原位角膜磨镶术(LASIK)患者的角膜扩张风险评分系统(ERSS)计算PRK术后角膜扩张的风险。还评估了组织改变百分比(PTA)。
年龄、残余散光(RSB)和等效球镜度数的ERSS评分为零的眼分别占66%、86%和86%。60%的眼角膜厚度测量风险评分为2,16%的眼角膜厚度测量风险评分为3或4。41%的眼角膜地形图风险评分为3,21%的眼角膜地形图风险评分为4。77%的眼角膜累积扩张风险评分≥4(高风险),86%的眼角膜累积扩张风险评分≥3(中高风险)。平均PTA为23.2±7.0%。除一只眼外,所有眼的PTA均<40%。
术前角膜地形图异常和角膜薄可能是PRK术后发生角膜扩张的重要危险因素。LASIK术后角膜扩张风险评分也与PRK术后发生角膜扩张的风险相关。