Hamm L F, Stull G A, Wolfe D R
Arch Phys Med Rehabil. 1987 Mar;68(3):165-9.
The response to early graded exercise testing (GXT) was studied in 227 patients at a mean of 15.3 days after myocardial revascularization surgery (MRS). GXT followed a modified Bruce protocol without multiples of resting energy expenditure (MET) restrictions and a target heart rate (HR) of 90% of age-predicted maximal HR. The decision as to precisely when to administer the GXT after surgery was made on an individual case basis by the cardiovascular surgeon and the attending cardiologist. For the data analysis, patients were grouped according to the number of days the GXT was administered after surgery: group 1, 7 to 14 days (n = 164); group 2, 15 to 28 days (n = 46); and group 3, greater than 28 days (n = 17). The use of beta blockers was also determined on an individual case basis by the attending cardiologist rather than on a random basis. Ninety-seven of the 227 patients were on beta blockers. Ventricular ectopic activity (VEA), ST-segment changes (STTC), peak HR, peak systolic blood pressure (SBP), peak rate-pressure product (RPP), and peak METs were assessed during exercise. No major complications occurred during testing. Approximately two thirds (67.4%) of the tests were terminated voluntarily by the patient, and 22.5% were stopped by the attending physician. Only 10.1% of the subjects reached the target HR. Chi-square analysis failed to reveal any association between time of testing after surgery and either STTC or VEA. Analysis of variance failed to reveal any effects of group or beta blocker on peak METs attained during GXT; however, patients not using beta blocker medication attained higher peak HR, SBP, and RPP.(ABSTRACT TRUNCATED AT 250 WORDS)
对227例心肌血运重建术后平均15.3天的患者进行了早期分级运动试验(GXT)反应的研究。GXT遵循改良的布鲁斯方案,无静息能量消耗(MET)倍数限制,目标心率(HR)为年龄预测最大心率的90%。心血管外科医生和主治心脏病专家根据具体病例决定术后何时进行GXT。数据分析时,患者按术后进行GXT的天数分组:第1组,7至14天(n = 164);第2组,15至28天(n = 46);第3组,大于28天(n = 17)。β受体阻滞剂的使用也由主治心脏病专家根据具体病例决定,而非随机使用。227例患者中有97例使用β受体阻滞剂。运动期间评估室性异位活动(VEA)、ST段改变(STTC)、峰值心率、收缩压峰值(SBP)、心率血压乘积峰值(RPP)和峰值METs。测试期间未发生重大并发症。约三分之二(67.4%)的测试由患者自愿终止,22.5%由主治医生终止。只有10.1%的受试者达到目标心率。卡方分析未发现术后测试时间与STTC或VEA之间存在任何关联。方差分析未发现分组或β受体阻滞剂对GXT期间达到的峰值METs有任何影响;然而,未使用β受体阻滞剂药物的患者达到了更高的峰值心率、收缩压和心率血压乘积。(摘要截断于250字)