Wamala Isaac, Roche Ellen T, Pigula Frank A
a Klinik für Herz- , Thorax- und Gefäßchirurgie, Deutsches Herzzentrum Berlin , Berlin , Germany.
b Discipline of Biomedical Engineering , College of Engineering and Informatics, National University of Ireland , Galway , Ireland.
Expert Rev Cardiovasc Ther. 2017 Oct;15(10):767-774. doi: 10.1080/14779072.2017.1366313. Epub 2017 Aug 23.
Robots have been employed in cardiovascular therapy as surgical tools and for automation of hospital systems. Soft robots are a new kind of robot made of soft deformable materials, that are uniquely suited for biomedical applications because they are inherently less likely to injure body tissues and more likely to adapt to biological environments. Awareness of the soft robotic systems under development will help promote clinician involvement in their successful clinical translation. Areas covered: The most advanced soft robotic systems, across the size scale from nano to macro, that have shown the most promise for clinical application in cardiovascular therapy because they offer solutions where a clear therapeutic need still exists. We discuss nano and micro scale technology that could help improve targeted therapy for cardiac regeneration in ischemic heart disease, and soft robots for mechanical circulatory support. Additionally, we suggest where the gaps in the technology currently lie. Expert commentary: Soft robotic technology has now matured from the proof-of-concept phase to successful animal testing. With further refinement in materials and clinician guided application, they will be a useful complement for cardiovascular therapy.
机器人已被用作心血管治疗的手术工具,并用于医院系统的自动化。软机器人是一种由柔软可变形材料制成的新型机器人,因其本质上不太可能损伤身体组织且更有可能适应生物环境,所以特别适合生物医学应用。了解正在开发的软机器人系统将有助于促进临床医生参与其成功的临床转化。涵盖领域:从纳米到宏观尺寸范围内最先进的软机器人系统,这些系统在心血管治疗的临床应用中显示出了最大的潜力,因为它们为仍存在明确治疗需求的领域提供了解决方案。我们讨论了有助于改善缺血性心脏病心脏再生靶向治疗的纳米和微米级技术,以及用于机械循环支持的软机器人。此外,我们指出了目前该技术存在的差距。专家评论:软机器人技术现已从概念验证阶段发展到成功的动物测试阶段。随着材料的进一步优化和临床医生指导下的应用,它们将成为心血管治疗的有益补充。