Chen Chen, Shen Xiaofeng, Wang Jiangping, Zhang Zhigang, Li Yuwei, Chen Hua
Department of Orthopaedics, Yanling Hospital of Traditional Chinese Medicine, 27 Huadudadao Road, 461000, Yanling, Henan, China.
Department of Orthopaedics, Suzhou Affiliated Hospital of Nanjing University of Chinese Medicine, 889 Wuzhongxi Road, 215009, Suzhou, Jiangsu, China.
Orthopade. 2017 Oct;46(10):855-863. doi: 10.1007/s00132-017-3455-x.
The aim of the study was to compare the extent of pain reduction with kyphoplasty (KP) and vertebroplasty (VP) in the treatment of osteoporotic vertebral compression fractures (OVCF) using a visual analog scale (VAS).
A computerized database search was performed to compare pain relief from VP and KP in OVCF. The available literature was analysed to quantify the amount of pain reduction using VAS as the primary outcome.
A total of 10 studies encompassing 902 patients met the inclusion criteria. Subgroup meta-analyses were performed according to the study design. VAS for the KP group was not significant compared with the VP group at 1 week, 1 month, and 6 months. Pain relief in the KP group was greater than that in the VP group at 12 months and 2 years.
KP is superior to VP in patients requiring pain relief. More large-scale, double-blinded controlled trials are necessary in order to quantify the pain relief afforded by VP more precisely.
本研究旨在使用视觉模拟评分法（VAS）比较椎体后凸成形术（KP）和椎体成形术（VP）在治疗骨质疏松性椎体压缩骨折（OVCF）时的疼痛减轻程度。
进行计算机数据库检索，以比较OVCF中VP和KP的疼痛缓解情况。分析现有文献，以VAS作为主要结局指标来量化疼痛减轻的程度。
共有10项研究（涉及902例患者）符合纳入标准。根据研究设计进行亚组荟萃分析。在1周、1个月和6个月时，KP组的VAS与VP组相比无显著差异。在12个月和2年时，KP组的疼痛缓解程度大于VP组。
在需要缓解疼痛的患者中，KP优于VP。为了更精确地量化VP所带来的疼痛缓解效果，有必要进行更多大规模、双盲对照试验。
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