枕骨中的异位小脑组织：一例报告
Ectopic cerebellar tissue in the occipital bone: a case report.
作者信息
Kawashima Mariko, Kobayashi Masahito, Ishizawa Keisuke, Fujimaki Takamitsu
机构信息
Department of Neurosurgery, Saitama Medical University Hospital, 38 Morohongo, Moroyama-machi, Iruma, Saitama, 350-0495, Japan.
Department of Pathology, Saitama Medical University Hospital, Saitama, Japan.
出版信息
J Med Case Rep. 2017 Aug 21;11(1):231. doi: 10.1186/s13256-017-1394-0.
BACKGROUND
Ectopic cerebellar tissue located distantly from the normal cerebellum is very rare, and its pathophysiology remains to be elucidated.
CASE PRESENTATION
We report an extremely rare case of intraosseous ectopic cerebellum detected incidentally at suboccipital craniotomy in a 46-year-old Japanese woman with hemifacial spasm. She had a small bone defect in the occipital bone, which contained a tiny area of soft tissue surrounded by cerebrospinal fluid connecting to the normal subarachnoid space through a dural opening. Histopathology demonstrated cerebellar cortex tissue consisting of molecular and granular cell layers.
CONCLUSIONS
This is the first report of glioneuronal ectopia within the skull bone separated from normal brain tissue, and it is important to distinguish this entity from other osteolytic lesions.
背景
远离正常小脑的异位小脑组织非常罕见，其病理生理学仍有待阐明。
病例报告
我们报告了一例极其罕见的骨内异位小脑病例，该病例在一名46岁患有半面痉挛的日本女性枕下开颅手术中偶然发现。她枕骨有一个小骨缺损，其中包含一小片软组织，周围是脑脊液，通过硬脑膜开口与正常蛛网膜下腔相连。组织病理学显示小脑皮质组织由分子层和颗粒细胞层组成。
结论
这是首例颅骨内与正常脑组织分离的神经胶质神经元异位的报告，将该实体与其他溶骨性病变区分开来很重要。
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