Ramdass Adesh A, Yao Mike, Natarajan Suneetha, Bakshi Parampreet K
Department of Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, NY, USA.
Department of Otolaryngology, Icahn School of Medicine at Mount Sinai, Elmhurst Hospital Center, Elmhurst, NY, USA.
Am J Case Rep. 2017 Aug 21;18:908-911. doi: 10.12659/ajcr.904084.
BACKGROUND Vagus nerve schwannoma is a benign neoplasm that usually presents as an asymptomatic slow growing mass, and its presentation as a neck mass is rare. The diagnosis can be difficult to make and complete surgical excision is challenging due to the proximity of the vagus nerve fibers from which it originates. The most common symptom associated with vagus nerve schwannoma arising in the neck is hoarseness due to vocal cord palsy. CASE REPORT We report a case of a 55-year-old woman who presented to the clinic complaining of throat irritation and feeling of something stuck in her throat for the past three months. On examination, a bulging left parapharyngeal mass was noted, displacing the left tonsil and uvula medially. A contrast-enhanced computed tomography (CT) scan of the neck showed a large, hypervascular soft tissue mass with splaying of the left internal carotid artery. Intraoperatively, the tumor was found to be arising from the vagus nerve. Macroscopic surgical pathology examination showed a tan-red, ovoid, and firm mass. Histopathology showed a benign spindle cell tumor with Antoni A areas with palisading cell nuclei and some degenerative change, confirming the diagnosis of vagus nerve schwannoma. CONCLUSIONS Vagus nerve schwannomas should be distinguished from other tumors that arise in the neck before planning surgery, to minimize the risk of nerve injury. Physicians need to be aware of the differential diagnosis of a neck mass, investigations required, the surgical treatment and the potential postoperative complications.
背景 迷走神经鞘瘤是一种良性肿瘤,通常表现为无症状的缓慢生长肿块,以颈部肿块形式出现较为罕见。其诊断可能困难,由于其起源的迷走神经纤维位置临近,完整手术切除具有挑战性。颈部迷走神经鞘瘤最常见的相关症状是声带麻痹导致的声音嘶哑。病例报告 我们报告一例55岁女性,她到诊所就诊,主诉在过去三个月里喉咙有刺激感和有东西卡在喉咙里的感觉。检查时,发现左侧咽旁有一隆起肿块,将左侧扁桃体和悬雍垂向内推移。颈部增强计算机断层扫描(CT)显示一个大的、高血管软组织肿块,左侧颈内动脉受压移位。术中发现肿瘤起源于迷走神经。宏观手术病理检查显示为棕红色、卵圆形、质地坚实的肿块。组织病理学显示为良性梭形细胞瘤,有呈栅栏状细胞核的Antoni A区和一些退行性改变,确诊为迷走神经鞘瘤。结论 在计划手术前,应将迷走神经鞘瘤与颈部出现的其他肿瘤区分开来,以尽量降低神经损伤风险。医生需要了解颈部肿块的鉴别诊断、所需检查、手术治疗及潜在术后并发症。