一名患有慢性粒细胞白血病的年轻男性的单侧乳腺增生
Unilateral Gynaecomastia in a Young Man with Chronic Myeloid Leukemia.
作者信息
Jain Ankur, Varma Subhash, Garg Rashi, Malhotra Pankaj
机构信息
Department of Medicine, 4th floor Nehru Hospital, PGIMER, Chandigarh, 160012 India.
Department of Cytology and Gynecological Pathology, PGIMER, Chandigarh, India.
出版信息
Indian J Hematol Blood Transfus. 2017 Sep;33(3):448-450. doi: 10.1007/s12288-016-0762-z. Epub 2016 Dec 19.
Male reproductive issues are frequently overlooked in patients of chronic myeloid leukemia (CML) on imatinib therapy. Current article describes a young man with CML on imatinib mesylate since 13 years who presented to us with painful left sided breast swelling. Mammography and fine needle aspiration cytology confirmed the diagnosis of gynaecomastia and hormone profile revealed low testosterone levels. Gynaecomastia was attributed to imatinib related hypogonadism. Gynaecomastia improved after hormone replacement therapy. Need for long term monitoring of reproductive hormones in patients of CML on imatinib therapy is emphasized in this report.
慢性粒细胞白血病（CML）患者接受伊马替尼治疗时，男性生殖问题常常被忽视。本文描述了一名自13年前开始接受甲磺酸伊马替尼治疗的CML青年男性，他因左侧乳房疼痛性肿胀前来就诊。乳房X线摄影和细针穿刺细胞学检查确诊为男性乳腺增生，激素水平检测显示睾酮水平低下。男性乳腺增生归因于伊马替尼相关的性腺功能减退。激素替代治疗后男性乳腺增生有所改善。本报告强调了对接受伊马替尼治疗的CML患者生殖激素进行长期监测的必要性。
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