McFadden E R
Respiration. 1986;50 Suppl 2:97-102. doi: 10.1159/000195107.
Long-acting beta 2-selective agonists have become a major form of therapy of reversible airway obstruction. Modern agents are effective by all routes of administration and can both eliminate bronchospasm as well as prevent its occurrence. Many drugs such as albuterol, terbutaline and fenoterol have similar pharmacologic profiles, and there is frequently little to choose between them. The majority of the available data indicate that aerosol therapy produces as much bronchodilation as the oral and parenteral routes with much fewer side effects.
长效β2 选择性激动剂已成为可逆性气道阻塞的主要治疗方式。现代制剂通过所有给药途径均有效，既能消除支气管痉挛，又能预防其发生。许多药物如沙丁胺醇、特布他林和非诺特罗具有相似的药理特性，它们之间往往没有太大区别。大多数现有数据表明，气雾剂疗法产生的支气管扩张效果与口服和胃肠外途径相同，但副作用要少得多。
