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2017年美国临床肿瘤学会(ASCO)年会报道的软组织肉瘤和胃肠道间质瘤(GIST)试验亮点。

Highlights in soft tissue sarcomas and gastrointestinal stromal tumours (GIST) trials reported at ASCO 2017 Annual Meeting.

作者信息

Frezza Anna Maria, Stacchiotti Silvia, Gronchi Alessandro

机构信息

Department of Cancer Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy.

出版信息

BMC Med. 2017 Aug 22;15(1):160. doi: 10.1186/s12916-017-0931-4.

Abstract

Herein, we summarise the results of the most relevant studies presented at the 2017 ASCO Annual Meeting in the field of soft tissue sarcomas (STSs) and gastrointestinal stromal tumours (GISTs). Innovations on the management of localised disease, highlights from the different experiences in the metastatic setting and large studies on rare histologies will be included. Special attention will be paid to results on immunotherapy, antiangiogenics use in histology with limited sensitivity to standard chemotherapy and new compounds. The preliminary results on the impact of the next generation sequencing in the everyday management of STS and GIST patients will be also discussed.

摘要

在此,我们总结了在2017年美国临床肿瘤学会(ASCO)年会上发表的软组织肉瘤(STS)和胃肠道间质瘤(GIST)领域最相关研究的结果。将包括局部疾病管理方面的创新、转移性疾病不同经验的亮点以及罕见组织学的大型研究。将特别关注免疫治疗的结果、在对标准化疗敏感性有限的组织学中使用抗血管生成药物以及新化合物。还将讨论下一代测序对STS和GIST患者日常管理影响的初步结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f257/5568712/255ba228e6c7/12916_2017_931_Fig1_HTML.jpg

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