新型自修复牙科水门汀微胶囊用于间接修复。

Novel self-healing dental luting cements with microcapsules for indirect restorations.

机构信息

Department of Prosthodontics, School of Stomatology, Shandong University, Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, 250012, China.

Oral Implantology Center, Jinan Stomatological Hospital, Jinan, 250001, China.

出版信息

J Dent. 2017 Nov;66:76-82. doi: 10.1016/j.jdent.2017.08.006. Epub 2017 Aug 18.

DOI:10.1016/j.jdent.2017.08.006

PMID:28826985

Abstract

OBJECTIVES

Dental luting cements are widely used to bond indirect restorations to teeth. Microcracks often lead to cement failures. The objectives of this study were to develop the first self-healing luting cement, and investigate dentin bond strength, mechanical properties, crack-healing, and self-healing durability in water-aging for 6 months.

METHODS

Microcapsules of poly(urea-formaldehyde) (PUF) shells with triethylene glycol dimethacrylate (TEGDMA) as healing liquid were synthesized. Cement contained bisphenol A glycidyl dimethacrylate, TEGDMA, 4-methacryloyloxyethyl trimellitic and glass fillers. Microcapsules were added at 0%, 2.5%, 5%, 7.5%, 8.5%, 9.5% and 10%. Dentin shear bond strength was measured using extracted human teeth. Flexural strength and elastic modulus were measured. Single edge V-notched beams were used to measure fracture toughness (K) and self-healing. Specimens were water-aged at 37°C for 6 months and then tested for self-healing durability.

RESULTS

Adding 7.5% microcapsules into cement achieved effective self-healing, without adverse effects on dentin bond strength and virgin mechanical properties (p>0.1). Excellent self-healing of 68%-77% recovery was obtained. Six months of water-aging did not decrease the self-healing efficiency, compared to 1 d (p>0.1), indicating that the self-healing property did not degrade in water-aging.

CONCLUSIONS

A self-healing dental luting cement was developed for the first time. It contained fine microcapsules and exhibited an excellent self-healing efficiency, even after being immersed in water for 6 months.

CLINICAL SIGNIFICANCE

The self-healing cement is promising for cementing crowns and bridges and other adhesive cement applications, to heal cracks and increase restoration longevity.

摘要

目的

牙科水门汀广泛用于将间接修复体粘结到牙齿上。微裂纹常导致水门汀失效。本研究的目的是开发首款自修复水门汀，并研究牙本质粘结强度、力学性能、裂纹愈合以及在 6 个月水老化后的自修复耐久性。

方法

合成了具有三甘醇二甲基丙烯酸酯（TEGDMA）作为愈合液的聚（脲-甲醛）（PUF）壳微胶囊。水门汀含有双酚 A 缩水甘油二甲基丙烯酸酯、TEGDMA、4-甲基丙烯酰氧基乙基偏苯三甲酸和玻璃填料。微胶囊的添加量分别为 0%、2.5%、5%、7.5%、8.5%、9.5%和 10%。使用提取的人牙测量牙本质剪切粘结强度。测量弯曲强度和弹性模量。使用单边 V 型缺口梁测量断裂韧性（K）和自修复性。将试件在 37°C 下进行为期 6 个月的水老化，然后测试自修复耐久性。