痴呆症的物理模型。
A physical model for dementia.
作者信息
Sotolongo-Costa O, Gaggero-Sager L M, Becker J T, Maestu F, Sotolongo-Grau O
机构信息
CInC-(IICBA), Universidad Autónoma del Estado de Morelos, 62209 Cuernavaca, Morelos, Mexico.
CIICAP-(IICBA), Universidad Autónoma del Estado de Morelos, 62209 Cuernavaca, Morelos, Mexico.
出版信息
Physica A. 2017 Apr 15;472:86-93. doi: 10.1016/j.physa.2016.12.086. Epub 2017 Jan 4.
Abstract
Aging associated brain decline often result in some kind of dementia. Even when this is a complex brain disorder a physical model can be used in order to describe its general behavior. A probabilistic model for the development of dementia is obtained and fitted to some experimental data obtained from the Alzheimer's Disease Neuroimaging Initiative. It is explained how dementia appears as a consequence of aging and why it is irreversible.
摘要
与衰老相关的大脑衰退常常会导致某种痴呆症。即便这是一种复杂的脑部疾病，也可以使用物理模型来描述其一般行为。我们获得了一个痴呆症发展的概率模型，并将其与从阿尔茨海默病神经影像倡议组织获得的一些实验数据进行拟合。文中解释了痴呆症是如何作为衰老的结果出现的，以及它为何不可逆转。
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