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环戊烯基脂肪酸:历史、生物活性与合成

Cyclopentenyl Fatty Acids: History, Biological Activity and Synthesis.

作者信息

Almahli Hadia

机构信息

Department of Chemistry, University of Oxford, Mansfield road, OX1 3TA, Oxford. United Kingdom.

出版信息

Curr Top Med Chem. 2017;17(26):2903-2912. doi: 10.2174/1568026617666170821125233.

Abstract

This review discusses the substantial cyclopentenyl fatty acid class of naturally occurring lipids. These compounds are historically important and have recently been shown to exhibit remarkable biological activity relevant to producing new antibiotic agents. Information about the history of cyclopentenyl fatty acids, their use in traditional and modern medicine, as well as biological activity, and methods for their synthesis are given.

摘要

本综述讨论了天然存在的环戊烯基脂肪酸类脂质。这些化合物具有重要的历史意义,最近已被证明具有与新型抗生素药物开发相关的显著生物活性。文中给出了环戊烯基脂肪酸的历史、其在传统医学和现代医学中的应用、生物活性以及合成方法等方面的信息。

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