Institute of Public Health Genomics, Department of Genetics and Cell Biology, Research Institute GROW (School for Oncology and Developmental Biology), Faculty of Health, Medicine and Life Sciences, University of Maastricht, 6200 MD Maastricht, the Netherlands.
Laboratory of Immunogenetics, Department of Medical Microbiology and Infection Control, VU University Medical Center, 1081 HX Amsterdam, the Netherlands.
Pathog Dis. 2017 Sep 29;75(7). doi: 10.1093/femspd/ftx081.
A reliable overview of data on the prevalence of Chlamydia trachomatis (CT) in Russia is lacking and needed. All the available data on CT prevalence were analyzed in a systematic literature review on CT prevalence in Russia, strengthened with data from the multicenter study among 1263 people in the second-largest Russian megalopolis, St. Petersburg, testing for CT DNA in urethral, anal, cervical and prostate samples. A total of 10 articles met the inclusion criteria. The overall average prevalence of genital CT infections in Russian populations ranged from 2.9% to 33%. Risk factors included being symptomatic (P = 0.004; in men P < 0.001), being younger than 30 years (P = 0.001) and being a man who has sex with men (MSM) (P = 0.0084). Main limitations included the lack of studies in MSM. CT prevalence was higher in the groups where urethral and prostate secretion samples were pooled (5.2%-7.3% vs 3.2% in the urethra only). The data on CT prevalence in a range of Russian populations are analyzed and reported. Prostate secretions represent an additional sampling material for the study of CT infection in men. CT detection in some settings in St. Petersburg yielded levels of reliability comparable with internationally available tests. The initiation of screening programs for Chlamydia infections in Russia should be considered.
缺乏可靠的俄罗斯沙眼衣原体 (CT) 流行数据，因此需要进行这方面的研究。在对俄罗斯沙眼衣原体流行情况进行的系统文献综述中，对所有可用的沙眼衣原体流行数据进行了分析，并结合了在俄罗斯第二大城市圣彼得堡对 1263 人进行的多中心研究的数据，该研究对尿道、肛门、宫颈和前列腺样本中的沙眼衣原体 DNA 进行了检测。共有 10 篇文章符合纳入标准。俄罗斯人群中生殖道 CT 感染的总体平均流行率为 2.9%至 33%。危险因素包括有症状（P=0.004；男性 P<0.001）、年龄小于 30 岁（P=0.001）和男男性行为者（MSM）（P=0.0084）。主要限制因素包括缺乏对 MSM 的研究。在合并尿道和前列腺分泌物样本的组中，CT 流行率更高（5.2%-7.3% 比仅尿道为 3.2%）。分析并报告了一系列俄罗斯人群中 CT 流行率的数据。前列腺分泌物是研究男性 CT 感染的另一种采样材料。在圣彼得堡的某些环境中进行 CT 检测的可靠性与国际上可用的检测方法相当。应考虑在俄罗斯启动衣原体感染筛查计划。
