Department of Pediatrics, Harbor-UCLA Medical Center, 1124 W.Carson Street, Torrance, CA 90502-2006, United States.
Prog Biophys Mol Biol. 2018 Jan;132:52-56. doi: 10.1016/j.pbiomolbio.2017.08.009. Epub 2017 Aug 19.
The nature of consciousness has been debated for centuries. It can be understood as part and parcel of the natural progression of life from unicellular to multicellular, calcium fluxes mediating communication within and between cells. Consciousness is the vertical integration of calcium fluxes, mediated by the Target of Rapamycin gene integrated with the cytoskeleton. The premise of this paper is that there is a fundamental physiologic integration of the organism with the environment that constitutes consciousness.
意识的本质已经争论了几个世纪。它可以被理解为从单细胞到多细胞生命自然进化的一部分,钙通量介导细胞内和细胞间的通讯。意识是钙通量的垂直整合,由与细胞骨架整合的雷帕霉素靶蛋白基因介导。本文的前提是,生物体与构成意识的环境之间存在着基本的生理整合。