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开放式鼻中隔鼻整形术中使用2-氰基丙烯酸辛酯和聚二氧六环酮板后发生的鼻中隔脓肿:病例系列

Postoperative Nasal Septal Abscess Following Use of 2-Octylcyanoacrylate and Polydioxanone Plate in Open Septorhinoplasty: A Case Series.

作者信息

Gall Ryan, Bevans Scott, Robitschek Jon

机构信息

1 Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.

2 Brooke Army Medical Center, Fort Sam Houston, Texas, USA.

出版信息

Ann Otol Rhinol Laryngol. 2017 Oct;126(10):688-692. doi: 10.1177/0003489417727013. Epub 2017 Aug 23.

Abstract

BACKGROUND

The employment of 2-octylcyanoacrylate adhesive (Dermabond) to assist graft placement in open septorhinoplasty has been increasingly used to stabilize cartilage grafts. Literature regarding this application has been mixed, with some showing the possibility of increased rates of inflammation, if not infection. We present an original comparative case series involving postoperative septal abscess formation adjacent to caudal strut grafting where both Dermabond and an absorbable polydioxanone (PDS) plate were used.

OBJECTIVE

To report an original comparative case series of patients who developed a postoperative septal abscess following open septorhinoplasty in the context of Dermabond application to affix cartilage to a PDS plate to facilitate caudal septal strut grafting.

DESIGN

Retrospective comparative series with relevant clinical photographs, culture studies, and surgical figures.

SETTING

Tertiary medical treatment facility.

RESULTS

Two patients underwent primary open septorhinoplasty with placement of an autologous caudal septal extension graft, which was stabilized using a PDS plate and secured into position using both Dermabond and PDS suture. Postoperatively, both patients presented a nasal septal abscess at an average of 8 weeks that required serial drainage and subsequent removal of the PDS plate in 1 of the patients. Cultures demonstrated mixed flora as well as Proteus mirabilis, previously unreported in the nasal septal abscess literature. In comparison to 8 patients who underwent reconstruction with PDS plate alone (without Dermabond application), this represents a relative risk of 15 ( P value = .053) for a septal abscess complication when Dermabond is employed .

CONCLUSIONS

We present an original case series on our limited, though impactful experience with PDS plate reconstruction using Dermabond to facilitate caudal septal graft placement in open septorhinoplasty. In conjunction with previously reported case series, which demonstrated elevated risk of prolonged inflammation and infection, we would recommend avoidance of subcutaneous Dermabond as an adjunct, particularly in combination with PDS plate utilization.

摘要

背景

在开放式鼻中隔成形术中使用2-氰基丙烯酸辛酯粘合剂(德美邦)辅助移植片放置越来越多地用于稳定软骨移植片。关于这种应用的文献说法不一,一些文献表明即使没有感染,也有炎症发生率增加的可能性。我们展示了一个原始的对比病例系列,涉及在尾状支柱移植附近术后鼻中隔脓肿形成的情况,其中同时使用了德美邦和可吸收的聚二氧六环酮(PDS)板。

目的

报告一个原始的对比病例系列,这些患者在开放式鼻中隔成形术中将软骨固定到PDS板上以促进鼻中隔尾状支柱移植时使用了德美邦,术后发生了鼻中隔脓肿。

设计

带有相关临床照片、培养研究和手术图片的回顾性对比系列。

地点

三级医疗设施。

结果

两名患者接受了初次开放式鼻中隔成形术并放置自体鼻中隔尾状延伸移植片,该移植片使用PDS板稳定,并使用德美邦和PDS缝线固定到位。术后,两名患者平均在8周时出现鼻中隔脓肿,需要进行系列引流,其中1例患者随后取出了PDS板。培养结果显示为混合菌群以及奇异变形杆菌,这在鼻中隔脓肿文献中此前未被报道。与仅使用PDS板(未使用德美邦)进行重建的8名患者相比,使用德美邦时鼻中隔脓肿并发症的相对风险为15(P值=0.053)。

结论

我们展示了一个原始病例系列,介绍了我们在开放式鼻中隔成形术中使用德美邦促进鼻中隔尾状移植片放置的有限但有影响力的PDS板重建经验。结合先前报道的病例系列,其显示出长期炎症和感染风险升高,我们建议避免将皮下德美邦作为辅助手段,特别是与PDS板联合使用时。

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