Becker R C, Giuliani M, Savage R A, Weick J K
J Surg Oncol. 1987 May;35(1):13-8. doi: 10.1002/jso.2930350104.
Over a 14-month period at the Cleveland Clinic Foundation, 424 strains of Clostridium were isolated; of these, 52 strains were Clostridium perfringens isolated from 41 patients. Eight strains of C. perfringens were isolated from the blood of six patients; five of these patients had neoplastic disease and three developed massive intravascular hemolysis with rapidly developing shock and death. Clinical details are given on three patients with fatal Clostridium perfringens sepsis, and the nature of presentation and pathophysiologic mechanisms are discussed.
在克利夫兰诊所基金会为期14个月的时间里，共分离出424株梭菌；其中，从41名患者中分离出52株产气荚膜梭菌。从6名患者的血液中分离出8株产气荚膜梭菌；这些患者中有5名患有肿瘤疾病，3名发生了大规模血管内溶血，并迅速发展为休克和死亡。文中给出了3例产气荚膜梭菌败血症致死患者的临床细节，并对其临床表现的性质和病理生理机制进行了讨论。
