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Short-term side effects and attitudes towards second donation: A comparison of related and unrelated haematopoietic stem cell donors.

作者信息

Pahnke Simon, Larfors Gunnar, Axdorph-Nygell Ulla, Fischer-Nielsen Anne, Haastrup Eva, Heldal Dag, Itälä-Remes Maija, Johansson Jan-Erik, Kauppila Marjut, Lenhoff Stig, Ljungman Per, Niittyvuopio Riita, Sandstedt Anna, Hägglund Hans

机构信息

Department of Haematology, Uppsala University Hospital, Uppsala, Sweden.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

出版信息

J Clin Apher. 2018 Jun;33(3):226-235. doi: 10.1002/jca.21576. Epub 2017 Aug 18.

DOI:10.1002/jca.21576
PMID:28833474
Abstract

The Nordic Register of Haematopoietic Stem Cell Donors (NRHSD) has registered related and unrelated donors from 10 transplant centres in Sweden, Norway, Finland and Denmark since 1998. We present a prospective, observational study of 1,957 donors, focusing mainly on the differences between related and unrelated donors. Related donors are reported to have more comorbidities, but similar side effects compared with unrelated donors. Side effects after BM or PBSC donation are generally of short duration and in this study no deaths, myocardial infarctions, splenic ruptures, or thromboembolic events are reported. Interestingly, related donors express more hesitancy towards donating again when asked 1 month after donation.

摘要

相似文献

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引用本文的文献

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Decision-making experience for second donation in unrelated hematopoietic stem cell donors: a descriptive qualitative study.非血缘造血干细胞捐献者二次捐献的决策经历：一项描述性定性研究
J Cancer Surviv. 2025 Aug 30. doi: 10.1007/s11764-025-01887-1.
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Hematopoietic Stem Cell Donors' Experiences of Information and Side-Effects During the First Year After Donation-A Swedish National Study.造血干细胞捐献者在捐献后第一年的信息及副作用体验——一项瑞典全国性研究
J Clin Apher. 2025 Aug;40(4):e70050. doi: 10.1002/jca.70050.
3
Cancer incidence in healthy Swedish peripheral blood stem cell donors.
健康的瑞典外周血造血干细胞供者的癌症发病率。
Bone Marrow Transplant. 2022 May;57(5):795-802. doi: 10.1038/s41409-022-01617-6. Epub 2022 Mar 7.