Bagliani Giuseppe, Della Rocca Domenico Giovanni, Di Biase Luigi, Padeletti Luigi
Arrhythmology Unit, Cardiology Department, Foligno General Hospital, Via Massimo Arcamone, 06034 Foligno (PG), Italy; Cardiovascular Diseases Department, University of Perugia, Piazza Menghini 1, 06129 Perugia Italy.
Department of Cardiovascular Medicine, University of Rome Tor Vergata, Rome, Italy; Texas Cardiac Arrhythmia Institute, St. David's Medical Center, 3000 N IH 35, Ste 700, Austin, TX 78705, USA.
Card Electrophysiol Clin. 2017 Sep;9(3):411-433. doi: 10.1016/j.ccep.2017.05.003.
The atrioventricular junction is a pivotal component of the cardiac conduction system, a key electrical relay site between the atria and the ventricles. The sophisticated functions carried out by the atrioventricular junction are possible for the presence of a complex apparatus made of specialized anatomic structures, cells with specific ion-channel expression, a well-organized spatial distribution of intercellular junctions (connexins), cells with intrinsic automatism, and a rich autonomic innervation. This article reviews the main anatomic and electrophysiologic features of the atrioventricular junction, with a focus on cardiac preexcitation.
房室交界区是心脏传导系统的关键组成部分,是心房和心室之间关键的电中继部位。房室交界区能够执行复杂功能,是因为存在由特殊解剖结构、具有特定离子通道表达的细胞、组织有序的细胞间连接(连接蛋白)空间分布、具有固有自律性的细胞以及丰富的自主神经支配所构成的复杂装置。本文综述了房室交界区的主要解剖和电生理特征,重点关注心脏预激。