Molecular and functional properties of beta-adrenergic receptors.

The beta-adrenergic receptors from various species have been extensively studied both at the pharmacologic and the structural level. Clinical observations may now be interpreted on the basis of mechanisms of interactions between catecholamines and their membrane receptors, regulation of these receptors by guanyl nucleotide binding proteins and stimulation of cyclic adenosine monophosphate production by adenylate cyclase.