Berthier J, Brakke K A, Gosselin D, Berthier E, Navarro F
Univ. Grenoble Alpes, F-38000 Grenoble, France; CEA LETI, MlNATEC Campus, F-38054 Grenoble, France.
Mathematics Department, Susquehanna University, Selinsgrove, PA 17870, USA.
Med Eng Phys. 2017 Oct;48:55-61. doi: 10.1016/j.medengphy.2017.08.004. Epub 2017 Aug 23.
Thread-based microfluidics has recently seen considerable developments in the domain of portable diagnostic systems, smart bandages and tissue engineering. Similarly to paper-based microfluidics, thread-based microfluidics uses the wicking of fibers to move fluids. It has the advantage of confining and guiding the fluid along the yarns in a one, two or three dimensional space. A global approach to the motion of fluids in yarns and fiber bundles has already been reported in the literature based on the Lucas-Washburn-Rideal law. However no detailed investigation of the flow pattern inside the bundle has been conducted, depending on the internal structure of the bundle. Especially when the bundle possesses heterogeneous wetting properties, such as two different wetting regions interior and exterior, different flow patterns may exist. In this work, we perform a theoretical and numerical analysis of the different flow regimes for homogenous and heterogeneous fiber bundles. It is demonstrated that a limited number of fibers is sufficient for thread-based capillary flows, and that a caging of the flow can be achieved by realizing a lyophobic envelope.
基于纤维的微流控技术最近在便携式诊断系统、智能绷带和组织工程领域取得了显著进展。与基于纸张的微流控技术类似，基于纤维的微流控技术利用纤维的毛细作用来移动流体。它具有在一维、二维或三维空间中沿着纱线限制和引导流体的优点。基于卢卡斯-沃什伯恩-里德尔定律，文献中已经报道了一种关于纱线和纤维束中流体运动的整体方法。然而，尚未根据纤维束的内部结构对束内的流动模式进行详细研究。特别是当纤维束具有非均匀的润湿性时，例如内部和外部有两个不同的润湿区域，可能会存在不同的流动模式。在这项工作中，我们对均匀和非均匀纤维束的不同流动状态进行了理论和数值分析。结果表明，有限数量的纤维足以实现基于纤维的毛细流动，并且通过实现疏液包壳可以实现对流动的限制。
