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蔓状神经囊尾蚴病的治疗。

Treatment of racemose neurocysticercosis.

作者信息

McClugage Samuel G, Lee Rachael A, Camins Bernard C, Mercado-Acosta Juan J, Rodriguez Martin, Riley Kristen O

机构信息

Department of Neurological Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.

Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.

出版信息

Surg Neurol Int. 2017 Aug 1;8:168. doi: 10.4103/sni.sni_157_17. eCollection 2017.

Abstract

BACKGROUND

Neurocysticercosis (NCC) is a common parasitic infection of the central nervous system, caused by the tapeworm . It is endemic to certain parts of the world, including Central America, South America, Asia, and Africa. The racemose form, characterized by extraparenchymal location, increased morbidity and mortality, and large loculated cystic lesions, is rarely seen in industrialized countries, such as the United States. The management of racemose neurocysticercosis (RNCC) differs from that of the typical parenchymal variant. The ideal course of treatment is debated by experts, but typically includes either surgical intervention with subsequent medical therapy or medical therapy alone.

CASE DESCRIPTION

We present the case of a 34-year-old male diagnosed with RNCC and treated successfully with surgical cyst drainage, resection, and subsequent medical therapy.

CONCLUSION

Currently, no standardized evidence-based protocol exists that dictate appropriate treatment for extraparenchymal or racemose NCC. We present a case of RNCC treated successfully with surgical and medical intervention. Further research encompassing well-designed clinical trials is necessary to delineate appropriate and standardized protocols for treatment of this disease.

摘要

背景

神经囊尾蚴病(NCC)是一种常见的中枢神经系统寄生虫感染,由绦虫引起。它在世界某些地区呈地方性流行,包括中美洲、南美洲、亚洲和非洲。葡萄状型神经囊尾蚴病以脑外部位、发病率和死亡率增加以及大的分叶状囊性病变为特征,在工业化国家如美国很少见。葡萄状神经囊尾蚴病(RNCC)的治疗与典型的实质型变体不同。治疗的理想方案存在争议,但通常包括手术干预后进行后续药物治疗或仅进行药物治疗。

病例描述

我们报告一例34岁男性被诊断为RNCC,并通过手术囊肿引流、切除及后续药物治疗成功治愈的病例。

结论

目前,尚无标准化的循证方案来指导脑外或葡萄状NCC的适当治疗。我们展示了一例通过手术和药物干预成功治疗的RNCC病例。有必要开展包括精心设计的临床试验在内的进一步研究,以确定针对该疾病的适当和标准化治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e60a/5551286/56993f778edc/SNI-8-168-g001.jpg

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