Jarkovský Jiří, Skřivanová Kateřina, Benešová Klára, Šnajdrová Lenka, Gregor Jakub, Peterková Hana, Bendová Marcela, Brančíková Dagmar, Elfmarková Nela, Svěrák Tomáš, Anderková Ľubomíra, Minář Luboš, Protivánková Markéta, Nedvěd Jan, Dušek Ladislav, Temoshok Lydia
Vnitr Lek. 2017 Summer;63(6):389-396.
This study examined the prognostic significance of breast cancer patients characteristics (coping strategies, BMI, age) and disease characteristics (stage of disease, relapse) with respect to quality of life (QoL) following treatment.Sample and settings: 120 breast cancer patients following treatment were recruited. Health-related QoL was assessed using the Czech version of FACT-B and SF-36; additionally, we used a life satisfaction questionnaire. Coping strategies were assessed using the SVF-78 method. In our sample of women, the average time from diagnosis to start of the study was 5.3 years.
Factors influencing QoL after treatment were analysed with univariate and multivariate linear regression.
Overall negative strategy defined in SVF-78 (Flight tendency, Resignation and Self-accusation) was found to be associated with lower scores of most components of used QoL methods, while Resignation was found as the most negatively influencing strategy. Active problem confrontation (Situation control and Positive self-instruction) was associated with better QoL. More advanced stages and recurrence were related to a significant decrease in QoL for certain components only.
Our findings suggest a significant predictive power of disease-related factors and of patients characteristics including coping strategies for QoL following treatment in Czech breast cancer survivors.Key words: breast cancer survivors - coping strategy - linear regression model - quality of life prediction - resignation.
本研究探讨了乳腺癌患者的特征(应对策略、体重指数、年龄)和疾病特征(疾病分期、复发情况)对治疗后生活质量(QoL)的预后意义。
招募了120名接受治疗后的乳腺癌患者。使用捷克语版的FACT-B和SF-36评估与健康相关的生活质量;此外,我们还使用了生活满意度问卷。采用SVF-78方法评估应对策略。在我们的女性样本中,从诊断到开始研究的平均时间为5.3年。
采用单因素和多因素线性回归分析治疗后影响生活质量的因素。
发现SVF-78中定义的总体消极策略(逃避倾向、顺从和自我指责)与所使用的生活质量方法的大多数组成部分得分较低相关,而顺从被发现是最具负面影响的策略。积极面对问题(情境控制和积极的自我指导)与更好的生活质量相关。仅某些组成部分的生活质量显著下降与更晚期阶段和复发有关。
我们的研究结果表明,在捷克乳腺癌幸存者中,疾病相关因素以及包括应对策略在内的患者特征对治疗后的生活质量具有显著的预测作用。
乳腺癌幸存者 - 应对策略 - 线性回归模型 - 生活质量预测 - 顺从