Räsänen Sami, Niemelä Mika, Nordström Tanja, Hakko Helinä, Haapea Marianne, Marshall Catherine A, Miettunen Jouko
Department of Psychiatry, Oulu University Hospital, Oulu, Finland.
Center for Life Course Health Research, University of Oulu, Oulu, Finland.
Early Interv Psychiatry. 2019 Apr;13(2):290-296. doi: 10.1111/eip.12479. Epub 2017 Aug 25.
The aim of this study was to investigate whether parental somatic illnesses during childhood increase the risk for later psychosis in the offspring. In addition, we examined which parental illnesses in particular are associated with increased risk of psychosis in the offspring.
The data of the Northern Finland Birth Cohort 1986 (NFBC 1986), included 9137 children born alive in northern Finland between the July 1, 1985, and the June 30, 1986. Information regarding the parents' somatic morbidity was collected through various healthcare registers up to age 28 of the cohort members.
Psychosis was diagnosed in 169 (1.8%) of the cohort members between the ages of 16 and 28. Accumulation of parental somatic diseases was related to later psychosis in the offspring. In addition, some specific somatic diagnostic groups of parents were emphasized in relation to psychosis in the offspring.
Our study findings indicated that parental somatic illness should be taken into account in the prevention of serious mental health problems in their offspring.
本研究旨在调查儿童期父母的躯体疾病是否会增加其后代日后患精神病的风险。此外，我们还研究了哪些父母疾病尤其与后代患精神病风险增加有关。
1986年芬兰北部出生队列（NFBC 1986）的数据包括1985年7月1日至1986年6月30日期间在芬兰北部出生的9137名活产儿童。通过各种医疗保健登记册收集了队列成员至28岁时父母的躯体疾病信息。
在16至28岁的队列成员中，有169人（1.8%）被诊断患有精神病。父母躯体疾病的累积与后代日后患精神病有关。此外，某些特定的父母躯体诊断组与后代患精神病有关。
我们的研究结果表明，在预防后代严重心理健康问题时应考虑父母的躯体疾病。
