Parry J Preston, Riche Daniel, Rushing John, Linton Brittany, Butler Vicki, Lindheim Steven R
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, University of Mississippi Medical Center, Jackson, Mississippi.
School of Pharmacy, University of Mississippi Medical Center, Jackson, Mississippi.
Fertil Steril. 2017 Oct;108(4):718. doi: 10.1016/j.fertnstert.2017.07.1159. Epub 2017 Aug 31.
To demonstrate a novel approach to office tubal patency assessment through infusing air into saline during flexible office hysteroscopy. We also provide data addressing pain and patient experience relative to hysterosalpingography (HSG).
Video presentation of clinical technique with supportive crossover data (Canadian Task Force classification II-1). Its University of Mississippi Medical Center Institutional Review Board protocol number is 2013-0230.
Academic hospital.
PATIENT(S): Women undergoing office hysteroscopy and ultrasound, with a subset also having HSG.
INTERVENTION(S): Air infusion into saline during office hysteroscopy.
MAIN OUTCOME MEASURE(S): The focus is on demonstrating how the technique appears and is performed, with supplemental Likert data addressing subjective pain and preference relative to HSG.
RESULT(S): When performed as described, this office technique has 98.3%-100% sensitivity to tubal occlusion and 83.7% specificity. The gentle technique is central to accurate outcomes, which is facilitated through use of a small-caliber (<3 mm), flexible hysteroscope and avoiding uterine overdistention. Patients are far more likely to report maximum discomfort with HSG. Among patients who also had HSG, 92% somewhat or strongly prefer hysteroscopic assessment. Also, 96% of patients reporting maximum discomfort with HSG had mild to no discomfort with the described technique.
CONCLUSION(S): Air-infused saline at flexible office hysteroscopy can accurately, gently, and rapidly assess tubal patency. Coupled with strong patient preference for this technique over HSG, it is a promising option for evaluating fertility.
NCT02005263.
展示一种在灵活的门诊宫腔镜检查过程中通过向盐水中注入空气来评估输卵管通畅性的新方法。我们还提供了与子宫输卵管造影术(HSG)相关的疼痛和患者体验数据。
临床技术的视频展示及支持性交叉数据(加拿大工作组分类II-1)。密西西比大学医学中心机构审查委员会方案编号为2013-0230。
学术医院。
接受门诊宫腔镜检查和超声检查的女性,其中一部分还接受了HSG检查。
在门诊宫腔镜检查期间向盐水中注入空气。
重点在于展示该技术的外观和操作方式,并通过补充李克特数据来反映相对于HSG的主观疼痛和偏好。
按照所述方法进行操作时,这种门诊技术对输卵管阻塞的敏感性为98.3%-100%,特异性为83.7%。轻柔的技术是获得准确结果的关键,使用小口径(<3mm)的柔性宫腔镜并避免子宫过度扩张有助于实现这一点。患者报告HSG时的最大不适感的可能性要大得多。在同时接受HSG检查的患者中,92%有点或强烈倾向于宫腔镜评估。此外,报告HSG检查时最大不适感的患者中有96%对所述技术只有轻微不适或无不适。
在灵活的门诊宫腔镜检查中注入空气的盐水能够准确、轻柔且快速地评估输卵管通畅性。再加上患者对该技术的偏好明显高于HSG,它是评估生育能力的一个有前景的选择。
NCT02005263。