Psychology Department, Wesleyan University, United States.
Department of Population Health, University of North Dakota, United States.
Addict Behav. 2018 Jan;76:161-168. doi: 10.1016/j.addbeh.2017.08.013. Epub 2017 Aug 18.
Depression is one of the most consistent risk factors implicated in both the course of escalating substance use behaviors and in the development of substance dependence symptoms, including those associated with marijuana use. In the present study, we evaluate if depression is associated with marijuana use disorder symptoms across the continuum of marijuana use frequency.
Data were drawn from six annual surveys of the National Survey of Drug Use and Health to include adults who reported using marijuana at least once in the past 30days (N=28,557).
After statistical control for sociodemographic characteristics and substance use behaviors including marijuana use, alcohol use, smoking, and use of illicit substances other than marijuana, depression was positively and significantly associated with each of the marijuana use disorder symptoms as well as the symptom total score. Adult marijuana users with depression were consistently more likely to experience marijuana use disorder symptoms and a larger number of symptoms, with the magnitude and direction of the relationship generally consistent across all levels of marijuana use frequency from 1day used in the past month to daily marijuana use.
Depression is a consistent risk factor for marijuana use disorder symptoms over and above exposure to marijuana suggesting that depressed individuals may represent an important subgroup in need of targeted substance use intervention.
抑郁症是与物质使用行为不断升级以及物质依赖症状发展（包括与大麻使用相关的症状）最一致的风险因素之一。在本研究中，我们评估了抑郁症是否与大麻使用障碍症状在大麻使用频率的连续体上有关。
数据来自国家药物使用与健康调查的六次年度调查，包括过去 30 天内至少使用过一次大麻的成年人（N=28557）。
在统计控制了社会人口特征和物质使用行为（包括大麻使用、酒精使用、吸烟以及除大麻以外的非法物质使用）后，抑郁症与大麻使用障碍的每种症状以及症状总分呈正相关且具有统计学意义。有抑郁症的成年大麻使用者更有可能经历大麻使用障碍症状和更多的症状，并且这种关系的大小和方向在过去一个月使用 1 天到每天使用大麻的所有大麻使用频率水平上基本一致。
抑郁症是大麻使用障碍症状的一个一致风险因素，超过了接触大麻的影响，这表明抑郁个体可能代表一个需要有针对性的物质使用干预的重要亚组。
