• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Verapamil inhibits cyclosporin metabolism.

作者信息

Lindholm A, Henricsson S

出版信息

Lancet. 1987 May 30;1(8544):1262-3. doi: 10.1016/s0140-6736(87)92710-3.

DOI:10.1016/s0140-6736(87)92710-3
PMID:2884392
Abstract
摘要

相似文献

1
Verapamil inhibits cyclosporin metabolism.维拉帕米抑制环孢素的代谢。
Lancet. 1987 May 30;1(8544):1262-3. doi: 10.1016/s0140-6736(87)92710-3.
2
Inhibition of cyclosporine metabolism by other drugs in vitro.其他药物在体外对环孢素代谢的抑制作用。
Transplant Proc. 1988 Apr;20(2 Suppl 2):569-71.
3
Cyclosporin A and verapamil have different effects on energy metabolism in multidrug-resistant tumour cells.环孢素A和维拉帕米对多药耐药肿瘤细胞的能量代谢有不同影响。
Br J Cancer. 1990 Jul;62(1):85-8. doi: 10.1038/bjc.1990.234.
4
Cyclosporin-verapamil interaction.环孢素-维拉帕米相互作用。
Br J Clin Pharmacol. 1988 Mar;25(3):402-3. doi: 10.1111/j.1365-2125.1988.tb03321.x.
5
Intracellular levels of two cyclosporin derivatives valspodar (PSC 833) and cyclosporin a closely associated with multidrug resistance-modulating activity in sublines of human colorectal adenocarcinoma HCT-15.两种环孢素衍生物（PSC 833）和环孢素A在人结肠腺癌HCT-15亚系中的细胞内水平与多药耐药调节活性密切相关。
Jpn J Cancer Res. 2001 Oct;92(10):1116-26. doi: 10.1111/j.1349-7006.2001.tb01067.x.
6
[Effect of verapamil on hepatorenal toxicity induced by cyclosporin].维拉帕米对环孢素诱导的肝肾毒性的影响
Arch Esp Urol. 1989 Nov-Dec;42(9):847-50.
7
Correspondence re: Xiu F. Hu et al., Combined use of cyclosporin A and verapamil in modulating multidrug resistance in human leukemia cell lines. Cancer Res., 50: 2953-2957, 1990.
Cancer Res. 1991 Mar 15;51(6):1749-50.
8
Chemosensitisation by verapamil and cyclosporin A in mouse tumour cells expressing different levels of P-glycoprotein and CP22 (sorcin).维拉帕米和环孢素A对表达不同水平P-糖蛋白和CP22（亲环蛋白A）的小鼠肿瘤细胞的化学增敏作用
Br J Cancer. 1990 Jul;62(1):89-95. doi: 10.1038/bjc.1990.235.
9
The effects of calcium channel blockers on cyclosporine and its metabolites in renal transplant recipients.钙通道阻滞剂对肾移植受者中环孢素及其代谢物的影响。
Ther Drug Monit. 1990 Jul;12(4):321-8.
10
Cyclosporin A and verapamil enhancement of daunorubicin-produced nucleolar protein B23 translocation in daunorubicin-resistant and -sensitive human and murine tumor cells.环孢菌素A和维拉帕米增强柔红霉素在耐药和敏感的人及鼠肿瘤细胞中诱导核仁蛋白B23易位的作用
Cancer Res. 1989 Feb 1;49(3):677-80.

引用本文的文献

1
The use of other drugs to allow a lower dosage of cyclosporin to be used. Therapeutic and pharmacoeconomic considerations.使用其他药物以降低环孢素的用药剂量。治疗及药物经济学考量。
Clin Pharmacokinet. 1997 May;32(5):357-67. doi: 10.2165/00003088-199732050-00002.
2
Clinically significant drug interactions with cyclosporin. An update.环孢素的具有临床意义的药物相互作用。最新进展。
Clin Pharmacokinet. 1996 Feb;30(2):141-79. doi: 10.2165/00003088-199630020-00004.
3
Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demethylation of verapamil in humans.
Naunyn Schmiedebergs Arch Pharmacol. 1995 Dec;353(1):116-21. doi: 10.1007/BF00168924.
4
Identification of P450 enzymes involved in metabolism of verapamil in humans.参与维拉帕米人体代谢的细胞色素P450酶的鉴定。
Naunyn Schmiedebergs Arch Pharmacol. 1993 Sep;348(3):332-7. doi: 10.1007/BF00169164.
5
The interaction of the calcium channel blockers verapamil and nifedipine with cyclosporin A in pediatric renal transplant patients.钙通道阻滞剂维拉帕米和硝苯地平与环孢素A在小儿肾移植患者中的相互作用。
Pediatr Nephrol. 1994 Aug;8(4):408-11. doi: 10.1007/BF00856514.
6
Isradipine. An update of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the treatment of mild to moderate hypertension.伊拉地平。其药效学、药代动力学特性及治疗轻至中度高血压疗效的最新进展。
Drugs. 1995 Apr;49(4):618-49. doi: 10.2165/00003495-199549040-00009.
7
Calcium antagonists. Drug interactions of clinical significance.钙拮抗剂。具有临床意义的药物相互作用。
Drug Saf. 1995 Sep;13(3):157-87. doi: 10.2165/00002018-199513030-00003.
8
The effect of combined therapy on the pharmacokinetics and pharmacodynamics of verapamil and propranolol in patients with angina pectoris.联合治疗对心绞痛患者维拉帕米和普萘洛尔药代动力学及药效学的影响。
Br J Clin Pharmacol. 1988 Mar;25(3):349-57. doi: 10.1111/j.1365-2125.1988.tb03313.x.
9
Adverse reactions and interactions of cyclosporin.环孢素的不良反应及相互作用。
Med Toxicol Adverse Drug Exp. 1988 Mar-Apr;3(2):107-27. doi: 10.1007/BF03259936.
10
[Effect of enalapril, furosemide and verapamil on cyclosporin concentration in whole blood].
Klin Wochenschr. 1988 Dec 1;66(23):1184-9. doi: 10.1007/BF01727667.