1 Laboratório de Psicofisiologia Sensorial, Departamento de Psicologia Experimental, Instituto de Psicologia, Universidade de São Paulo, São Paulo, Brazil.
2 Núcleo de Neurociências e Comportamento e Neurociências Aplicada, Universidade de São Paulo, São Paulo, Brazil.
Clin EEG Neurosci. 2018 May;49(3):159-170. doi: 10.1177/1550059417723804. Epub 2017 Aug 28.
The sweep visual evoked potential method (sVEP) is a powerful tool for measurement of visual acuity in infants. Despite the applicability and reliability of the technique in measuring visual functions the understanding of sVEP acuity maturation and how interocular difference of acuity develops in early infancy, as well as the availability of normality ranges, are rare in the literature. We measured binocular and monocular sVEPS acuities in 481 healthy infants aged from birth to 24 months without ophthalmological diseases. Binocular sVEP acuity was significantly higher than monocular visual acuities for almost all ages. Maturation of monocular sVEP acuity showed 2 longer critical periods while binocular acuity showed three maturation periods in the same age range. We found a systematic variation of the mean interocular acuity difference (IAD) range according to age from 1.45 cpd at birth to 0.31 cpd at 24 months. An additional contribution was the determination of sVEP acuity norms for the entire age range. We conclude that binocular and monocular sVEP acuities have distinct growth curves reflecting different maturation profiles for each function. Differences in IAD range shorten according to age and they should be considered in using the sVEP acuity measurements for clinical diagnosis as amblyopia.
扫频视觉诱发电位法（sVEP）是测量婴儿视力的有力工具。尽管该技术在测量视觉功能方面具有适用性和可靠性，但是 sVEP 视力成熟度以及双眼视力差异在早期婴儿期的发展方式，以及正常范围的可用性在文献中很少见。我们在 481 名无眼部疾病的健康婴儿中测量了双眼和单眼 sVEPs 视力，年龄从出生到 24 个月不等。对于几乎所有年龄段，双眼 sVEP 视力都明显高于单眼视力。单眼 sVEP 视力的成熟过程显示出 2 个较长的关键期，而双眼视力在相同的年龄范围内则显示出 3 个成熟期。我们发现，随着年龄的增长，平均双眼间视力差异（IAD）范围呈系统变化，从出生时的 1.45 cpd 到 24 个月时的 0.31 cpd。另一个贡献是确定了整个年龄范围内的 sVEP 视力标准。我们得出结论，双眼和单眼 sVEP 视力具有不同的增长曲线，反映了每种功能的不同成熟情况。IAD 范围的差异随着年龄的增长而缩短，在使用 sVEP 视力测量值进行临床诊断弱视时应予以考虑。
