[Application of carbon nanoparticles suspension injection in uremic patients with secondary hyperparathyroidism underwent total parathyroidectomy: 2 case report and literature review].

Total parathyroidectomy (PTX) can be used to treat secondary hyperparathyroidism (SHPT) in uremic patients, relieving the patient's osteolytic destruction. Complete resection of bilateral parathyroid glands is key to successful operation. Recently, 2 patients successfully received surgical treatment, in which carbon nanoparticles suspension injection were used. With the help of carbon nanoparticles suspension injection, all of the 4 hyperplastic parathyroid glands were found successfully. The parathyroid hormone(PTH) was significantly decreased after operations and the clinical symptoms were relieved simultaneously. We conclude that the use of carbon nanoparticles suspension injection is helpful for total parathyroidectomy operation in uremic patients with SHPT, which can protect the normal thyroid and recurrent laryngeal nerve.