睾丸女性化大鼠睾丸中缺乏一种23kd蛋白。
Absence of a 23 kd protein in testes of testicular feminization rat.
作者信息
Chan W Y, Bates J M, Rennert O M, Chung K W
出版信息
Life Sci. 1987 Jun 1;40(22):2169-73. doi: 10.1016/0024-3205(87)90007-5.
PMID:2884544
Abstract
Cryptorchid testes of testicular feminization rats are very low in zinc in spite of normal zinc status of the animals. Analysis of the cytosol of the cryptorchid testes by gel permeation chromatography showed decreased zinc binding by proteins eluted at fractions corresponding to 30,000 dalton. Further analysis by sodium dodecylsulphate polyacrylamide gel electrophoresis indicated the absence of a protein with molecular weight of 23,000.
摘要
睾丸雌性化大鼠的隐睾锌含量非常低，尽管动物的锌状态正常。通过凝胶渗透色谱法对隐睾的胞质溶胶进行分析，结果显示，在对应于30,000道尔顿的级分中洗脱的蛋白质与锌的结合减少。通过十二烷基硫酸钠聚丙烯酰胺凝胶电泳进一步分析表明，分子量为23,000的蛋白质不存在。
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