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非体外循环冠状动脉搭桥手术患者术前心脏左心室功能障碍与围手术期主动脉内球囊反搏的相关性

Association between Preoperative Cardiac Left Ventricular Dysfunction and Perioperative Intraaortic Balloon Pump in Patients Undergoing Off-Pump Coronary Artery Bypass Surgery.

作者信息

Kusumoto Go, Shigematsu Kenji, Iwashita Kouhei, Tominaga Kenji, Totoki Takaaki, Yamaura Ken

机构信息

Department of Anesthesiology, Fukuoka University School of Medicine, Fukuoka, Japan.

出版信息

Heart Surg Forum. 2017 Aug 25;20(4):E147-E152. doi: 10.1532/hsf.1808.

Abstract

BACKGROUND

Prophylactic use of intraaortic balloon pump (IABP) reduces hospital mortality in patients with left ventricular (LV) systolic dysfunction undergoing coronary artery bypass surgery (CABG); however, its association in patients with LV diastolic dysfunction is unclear. This retrospective study investigated the association between preoperative LV function and perioperative use of IABP in patients undergoing off-pump CABG (OPCAB) at a university hospital.

METHODS

100 consecutive patients who underwent OPCAB between January 1, 2011 and August 31, 2014 were studied. Preoperative LV function was categorized into four groups based on LV systolic and diastolic function determined with preoperative transthoracic echocardiography. The use of IABP was reviewed from medical records. The Mann-Whitney test, Pearson chi-square test, or Fisher exact test were used.

RESULTS

Patients were categorized into the following groups: normal LV function (n = 43), isolated LV systolic dysfunction (n = 13), isolated LV diastolic dysfunction (n = 21), and combined LV systolic and diastolic dysfunction (n = 14). Intraoperative IABP use was significantly more frequent in patients with isolated LV systolic dysfunction, isolated LV diastolic dysfunction, and combined LV systolic and diastolic dysfunction than in those with normal LV function (P < .05). Furthermore, IABP was used more frequently in patients who developed combined LV systolic and diastolic dysfunction postoperatively (P < .05). Conclusion: Not only the presence of preoperative systolic dysfunction but also LV diastolic dysfunction in the presence of normal LV systolic function were associated with increased use of IABP during and after OPCAB.

摘要

背景

预防性使用主动脉内球囊反搏(IABP)可降低接受冠状动脉旁路移植术(CABG)的左心室(LV)收缩功能不全患者的医院死亡率;然而,其在LV舒张功能不全患者中的相关性尚不清楚。这项回顾性研究调查了一所大学医院中接受非体外循环CABG(OPCAB)患者术前LV功能与IABP围手术期使用之间的相关性。

方法

研究了2011年1月1日至2014年8月31日期间连续接受OPCAB的100例患者。根据术前经胸超声心动图测定的LV收缩和舒张功能,将术前LV功能分为四组。从病历中回顾IABP的使用情况。使用Mann-Whitney检验、Pearson卡方检验或Fisher精确检验。

结果

患者分为以下几组:LV功能正常(n = 43)、孤立性LV收缩功能不全(n = 13)、孤立性LV舒张功能不全(n = 21)以及合并LV收缩和舒张功能不全(n = 14)。孤立性LV收缩功能不全、孤立性LV舒张功能不全以及合并LV收缩和舒张功能不全的患者术中IABP使用频率显著高于LV功能正常的患者(P <.05)。此外,术后发生合并LV收缩和舒张功能不全的患者IABP使用频率更高(P <.05)。结论:不仅术前存在收缩功能不全,而且在LV收缩功能正常的情况下存在LV舒张功能不全,均与OPCAB期间及术后IABP使用增加有关。

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