Petersson B
Ups J Med Sci. 1987;92(1):85-8. doi: 10.3109/03009738709178682.
Cysteamine is known to deplete the immunoreactive somatostatin content in different organs from rat and mouse. The aim of the present work was to test if cysteamine also affects the somatostatin content in guinea-pig islets, since guinea-pigs have a carbohydrate metabolism different from that of other laboratory animals. Cysteamine was injected to guinea-pigs and the pancreatic islets were isolated four hours later. Cysteamine was also incubated in vitro with isolated pancreatic islets from untreated guinea-pigs. Cysteamine depleted the somatostatin content in the pancreatic islets in both the in vivo and in vitro studies.
已知半胱胺会消耗大鼠和小鼠不同器官中免疫反应性生长抑素的含量。本研究的目的是测试半胱胺是否也会影响豚鼠胰岛中生长抑素的含量，因为豚鼠的碳水化合物代谢与其他实验动物不同。给豚鼠注射半胱胺，4小时后分离胰腺胰岛。半胱胺也与未处理豚鼠的分离胰腺胰岛进行体外孵育。在体内和体外研究中，半胱胺均消耗了胰腺胰岛中生长抑素的含量。
