Trattler William B, Majmudar Parag A, Donnenfeld Eric D, McDonald Marguerite B, Stonecipher Karl G, Goldberg Damien F
Center for Excellence in Eye Care, Miami, FL, USA.
Chicago Cornea Consultants, Chicago, IL, USA.
Clin Ophthalmol. 2017 Aug 7;11:1423-1430. doi: 10.2147/OPTH.S120159. eCollection 2017.
To determine the incidence and severity of dry eye as determined by the International Task Force (ITF) scale in patients being screened for cataract surgery.
This was a prospective, multi-center, observational study of 136 patients, at least 55 years of age, who were scheduled to undergo cataract surgery. The primary outcome measure was the incidence of dry eye as evaluated by grade on the ITF scale and secondary outcome measures include tear break-up time (TBUT), ocular surface disease index score, corneal staining with fluorescein, conjunctival staining with lissamine green, and a patient questionnaire to evaluate symptoms of dry eye.
Mean patient age was 70.7 years. A total of 73.5% of patients were Caucasian and 50% were female. Almost 60% had never complained of a foreign body sensation; only 13% complained of a foreign body sensation half or most of the time. The majority of patients (62.9%) had a TBUT ≤5 seconds, 77% of eyes had positive corneal staining and 50% of the eyes had positive central corneal staining. Eighteen percent had Schirmer's score with anesthesia ≤5 mm.
The incidence of dry eye in patients scheduled to undergo cataract surgery in a real-world setting is higher than anticipated.
确定在接受白内障手术筛查的患者中，根据国际工作组（ITF）量表判定的干眼发病率及严重程度。
这是一项针对136例年龄至少55岁、计划接受白内障手术患者的前瞻性、多中心观察性研究。主要结局指标是根据ITF量表分级评估的干眼发病率，次要结局指标包括泪膜破裂时间（TBUT）、眼表疾病指数评分、荧光素角膜染色、丽丝胺绿结膜染色，以及一份用于评估干眼症状的患者问卷。
患者平均年龄为70.7岁。共有73.5%的患者为白种人，50%为女性。近60%的患者从未抱怨有异物感；只有13%的患者在一半或大部分时间里抱怨有异物感。大多数患者（62.9%）的TBUT≤5秒，77%的眼睛角膜染色阳性，50%的眼睛中央角膜染色阳性。18%的患者麻醉后Schirmer试验评分≤5毫米。
在现实环境中，计划接受白内障手术的患者干眼发病率高于预期。
