Institute for Global Health & Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
University of North Carolina Project-China, Guangzhou, Guangdong, China.
AIDS Behav. 2018 Mar;22(3):701-710. doi: 10.1007/s10461-017-1893-4.
Quantifying HIV service provision along the HIV care continuum is increasingly important for monitoring and evaluating HIV interventions. We examined factors associated with linkage and retention in care longitudinally among MSM (n = 1974, 4933 person-years) diagnosed and living in Guangzhou, China, in 2008-2014. We measured longitudinal change of retention in care (≥2 CD4 tests per year) from linkage and antiretroviral therapy initiation (ART). We examined factors associated with linkage using logistic regression and with retention using generalized estimating equations. The rate of linkage to care was 89% in 2014. ART retention rate dropped from 71% (year 1) to 46% (year 2), suggesting that first-year retention measures likely overestimate retention over longer periods. Lower CD4 levels and older age predicted retention in ART care. These data can inform interventions to improve retention about some subgroups.
量化艾滋病护理连续体中的艾滋病毒服务提供情况对于监测和评估艾滋病毒干预措施越来越重要。我们研究了 2008-2014 年期间在中国广州诊断和生活的男男性行为者(n=1974,4933 人年)中,与纵向链接和维持治疗相关的因素。我们从开始接受抗逆转录病毒治疗(ART)时开始衡量维持治疗(每年至少进行 2 次 CD4 检测)的纵向变化。我们使用逻辑回归来评估与链接相关的因素,使用广义估计方程来评估与维持治疗相关的因素。2014 年的链接到治疗的比例为 89%。ART 的保留率从 71%(第 1 年)降至 46%(第 2 年),这表明第一年的保留率可能高估了更长时间的保留率。较低的 CD4 水平和年龄较大预示着 ART 治疗的保留率。这些数据可以为改善某些亚组的保留率的干预措施提供信息。