[射波刀®：葡萄膜黑色素瘤的新治疗选择]
[CyberKnife®: new treatment option for uveal melanoma].
作者信息
Mor J M, Semrau R, Baus W, Koch K R, Schaub F, Cursiefen C, Marnitz S, Heindl L M
机构信息
Zentrum für Augenheilkunde, Universität zu Köln, Kerpener Str. 62, 50924, Köln, Deutschland.
Klinik und Poliklinik für Strahlentherapie, Universität zu Köln, Köln, Deutschland.
出版信息
Ophthalmologe. 2018 Apr;115(4):302-308. doi: 10.1007/s00347-017-0560-5.
BACKGROUND
CyberKnife® stereotactic radiosurgery is a new treatment option for uveal melanoma.
OBJECTIVE
This review outlines the technique of robot-assisted CyberKnife® therapy, as well as the pros and cons in the treatment of uveal melanoma.
METHODS
The study provides a PubMed literature review and own preliminary clinical experiences.
RESULTS
CyberKnife® therapy for choroidal and ciliary body melanomas shows comparable results concerning local tumor control and overall survival matching those of conventional therapies. With only low complication rates, a high level of quality of life can be conserved by possible preservation of visual acuity as well as the ocular globe.
CONCLUSION
Stereotactic radiosurgery using CyberKnife® seems to be an efficient and safe therapeutic option for malignant melanomas affecting the choroid and ciliary body. Comparative studies with conventional radiation strategies are now a high priority.
背景
射波刀®立体定向放射外科是葡萄膜黑色素瘤的一种新的治疗选择。
目的
本综述概述了机器人辅助射波刀®治疗技术，以及治疗葡萄膜黑色素瘤的利弊。
方法
该研究提供了PubMed文献综述及自身初步临床经验。
结果
射波刀®治疗脉络膜和睫状体黑色素瘤在局部肿瘤控制和总生存率方面显示出与传统疗法相当的结果。并发症发生率低，通过可能保留视力和眼球，可以保持较高的生活质量。
结论
使用射波刀®的立体定向放射外科似乎是治疗累及脉络膜和睫状体的恶性黑色素瘤的一种有效且安全的治疗选择。目前，与传统放射治疗策略的比较研究是当务之急。
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