[Pharmacoethological analysis of the effects of thyroliberin and melanostatin in a model of anxious-defensive behavior in mice].
作者信息
Poshivalov V P, Iurkevich A V, Tsakhaev G A
出版信息
Biull Eksp Biol Med. 1987 Jun;103(6):681-3.
PMID:2885047
Abstract
Psychotropic properties of thyroliberin and melanostatin were studied on the model of timid-defensive behaviour of mice. Oligopeptides increased defensive behaviour and timidity, and decreased intraspecies sociability. GABA deficiency and dopaminergic system blockade increased timid-defensive behaviour of mice. Mobilizing activity of peptides on the agonistic behaviour (aggression and defense) may be explained by their anxiogenic properties.
摘要
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