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老年外科术后救援(GRAS)评分用于预测老年急诊普通外科患者的救援失败情况。

Geriatric rescue after surgery (GRAS) score to predict failure-to-rescue in geriatric emergency general surgery patients.

作者信息

Khan Muhammad, Azim Asad, O'Keeffe Terence, Jehan Faisal, Kulvatunyou Narong, Santino Chelsey, Tang Andrew, Vercruysse Gary, Gries Lynn, Joseph Bellal

机构信息

Division of Trauma, Critical Care, Emergency Surgery, and Burns, Department of Surgery, University of Arizona, Tucson, AZ, USA.

出版信息

Am J Surg. 2018 Jan;215(1):53-57. doi: 10.1016/j.amjsurg.2017.08.002. Epub 2017 Aug 15.

Abstract

BACKGROUND

Geriatric-patients(GP) undergoing emergency-general-surgery(EGS) are vulnerable to develop adverse-outcomes. Impact of patient-level-factors on Failure-to-Rescue(FTR) in EGS-GP remains unclear. Aim of our study was to determine factors associated with FTR(death from major-complication) and devise simple-bedside-score that predicts FTR in EGS-GP.

METHODS

3-year(2013-15) analysis of patients, age≥65y on acute-care-surgery-service and underwent EGS. Regression analysis used to analyze factors associated with FTR and natural-logarithm of significant odds-ratio used to calculate estimated-weights for each factor. Geriatric-Rescue-After-Surgery(GRAS)-score calculated for each-patient. AUROC used to assess model discrimination.

RESULTS

725 EGS-patients analyzed. 44.6%(n = 324) had major-complications. The FTR-rate was 11.5%. Overall-mortality rate was 15.3%. On regression, significant-factors with their estimated-weights were:Age≥80y(2), Chronic-Obstructive-Pulmonary-Disease(COPD)(1), Chronic-renal-failure(CRF)(2), Congestive-heart-failure(CHF)(1), Albumin<3.5(1) and ASA score>3(2). AUROC of score was 0.787.

CONCLUSION

GRAS-score is first score based on preoperative assessment that can reliably predict FTR in EGS-GP. Preoperative identification of patients at increased-risk of FTR can help in risk-stratification and timely-mobilization of resources for successful rescue of these patients.

摘要

背景

接受急诊普通外科手术(EGS)的老年患者(GP)容易出现不良后果。患者层面因素对EGS-GP中未能挽救(FTR)的影响尚不清楚。我们研究的目的是确定与FTR(因重大并发症死亡)相关的因素,并设计一种简单的床边评分来预测EGS-GP中的FTR。

方法

对在急性护理手术服务中年龄≥65岁且接受EGS的患者进行3年(2013 - 15年)分析。使用回归分析来分析与FTR相关的因素,并使用显著优势比的自然对数来计算每个因素的估计权重。为每位患者计算老年术后挽救(GRAS)评分。使用受试者工作特征曲线下面积(AUROC)来评估模型的辨别力。

结果

分析了725例EGS患者。44.6%(n = 324)发生了重大并发症。FTR率为11.5%。总死亡率为15.3%。回归分析显示,具有估计权重的显著因素为:年龄≥80岁(2)、慢性阻塞性肺疾病(COPD)(1)、慢性肾衰竭(CRF)(2)、充血性心力衰竭(CHF)(1)、白蛋白<3.5(1)和美国麻醉医师协会(ASA)评分>3(2)。评分的AUROC为0.787。

结论

GRAS评分是首个基于术前评估的评分,能够可靠地预测EGS-GP中的FTR。术前识别FTR风险增加的患者有助于进行风险分层,并及时调动资源以成功挽救这些患者。

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