Wang Di, Li Li, Wei Lei, Liu Yingying, Sun Shiren
Department of Nephrology, Xijing Hospital, Xi'an, Shaanxi, China.
Institute of Neurosciences, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Parasitol Int. 2017 Dec;66(6):802-805. doi: 10.1016/j.parint.2017.08.008. Epub 2017 Aug 26.
Acute postinfectious glomerulonephritis (GN) secondary to scabies were mainly documented as early as in 1980s, and in all these published cases no histopathological evidence of renal biopsy were reported regarding scabies and renal damage. The delay in scabies treatment can result in a greater risk of secondary bacterial infections that can become invasive and/or lead to severe post-infective complications such as post-streptococcal glomerulonephritis. In diagnostic procedures, the clinical presentation of scabies is often atypical especially in elderly people patients. However, early diagnosis is necessary to prevent disease progression. Here, we present a case of acute glomerulonephritis caused by scabies in a 79-year-old male patient who presented with papular rash, asthma, haematuria, proteinuria, hypertension and variable azotaemia. The aim is to provide more details of the clinical features and the histopathologic characteristics, and to increase the vigilance among physicians in patients with acute GN.
早在20世纪80年代就有疥疮继发急性感染后肾小球肾炎(GN)的记录,在所有这些已发表的病例中,均未报告肾活检有关疥疮与肾损害的组织病理学证据。疥疮治疗延迟会导致继发细菌感染风险增加,这些感染可能会扩散和/或导致严重的感染后并发症,如链球菌感染后肾小球肾炎。在诊断过程中,疥疮的临床表现通常不典型,尤其是在老年患者中。然而,早期诊断对于预防疾病进展至关重要。在此,我们报告一例79岁男性患者因疥疮引发急性肾小球肾炎的病例,该患者出现丘疹性皮疹、哮喘、血尿、蛋白尿、高血压和不同程度的氮质血症。目的是提供更多临床特征和组织病理学特征的细节,并提高医生对急性GN患者的警惕性。