肿瘤细胞的生物能量学：肿瘤细胞线粒体中的谷氨酰胺代谢 - Suppr

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Bioenergetics of tumor cells: glutamine metabolism in tumor cell mitochondria.

作者信息

Matsuno T

出版信息

Int J Biochem. 1987;19(4):303-7. doi: 10.1016/0020-711x(87)90002-4.

DOI:10.1016/0020-711x(87)90002-4

PMID:2885235

Abstract

摘要

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Bioenergetics of tumor cells: glutamine metabolism in tumor cell mitochondria.肿瘤细胞的生物能量学：肿瘤细胞线粒体中的谷氨酰胺代谢

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Mitochondrial metabolism of glutamine and glutamate and its physiological significance.谷氨酰胺和谷氨酸的线粒体代谢及其生理意义。

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[Metabolism of glutamic acid in brain mitochondria].[脑线粒体中谷氨酸的代谢]

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Mechanism of carrier-mediated glutamine transport across the inner mitochondrial membrane.载体介导的谷氨酰胺跨线粒体内膜转运的机制。

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Glutamate metabolism triggered by oxaloacetate in intact plant mitochondria.完整植物线粒体中草酰乙酸引发的谷氨酸代谢

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[The metabolism of glutamic acid and of glutamine in neoplasms and non-neoplastic tissues. 1. Study of reactions of transamination].[肿瘤组织与非肿瘤组织中谷氨酸和谷氨酰胺的代谢。1. 转氨基反应的研究]

Bull Assoc Fr Etud Cancer. 1960 Jan-Mar;47:108-18.

引用本文的文献

Design and evaluation of novel glutaminase inhibitors.新型谷氨酰胺酶抑制剂的设计与评估

Bioorg Med Chem. 2016 Apr 15;24(8):1819-39. doi: 10.1016/j.bmc.2016.03.009. Epub 2016 Mar 7.

Kidney-type glutaminase (GLS1) is a biomarker for pathologic diagnosis and prognosis of hepatocellular carcinoma.肾型谷氨酰胺酶（GLS1）是肝细胞癌病理诊断和预后的生物标志物。

Oncotarget. 2015 Apr 10;6(10):7619-31. doi: 10.18632/oncotarget.3196.

(13)C-Leucine-tracer-technique for in-vivo measurement of amino acids' metabolism by human colon carcinomas.（13）C-亮氨酸示踪技术在人结肠癌细胞内氨基酸代谢的活体测量中的应用。

Amino Acids. 1991 Jun;1(2):283-7. doi: 10.1007/BF00806927.

Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes.有丝分裂促进复合物/周期蛋白体-Cdh1 通过与人类 T 淋巴细胞向 S 期的转变协调糖酵解和谷氨酰胺分解作用。

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18868-73. doi: 10.1073/pnas.1012362107. Epub 2010 Oct 4.

'Why do tumour cells glycolyse?': from glycolysis through citrate to lipogenesis.“肿瘤细胞为何进行糖酵解？”：从糖酵解经柠檬酸到脂肪生成

Mol Cell Biochem. 2005 Dec;280(1-2):1-8. doi: 10.1007/s11010-005-8841-8.

Glutamine transport by vesicles isolated from tumour-cell mitochondrial inner membrane.从肿瘤细胞线粒体内膜分离的囊泡对谷氨酰胺的转运

Biochem J. 1995 Jun 1;308 ( Pt 2)(Pt 2):629-33. doi: 10.1042/bj3080629.

High malic enzyme activity in tumor cells and its cross-reaction with anti-pigeon liver malic enzyme serum.肿瘤细胞中苹果酸酶活性高及其与抗鸽肝苹果酸酶血清的交叉反应。

Mol Cell Biochem. 1988 Feb;79(2):171-9. doi: 10.1007/BF02424560.

Relevance of glutamine metabolism to tumor cell growth.谷氨酰胺代谢与肿瘤细胞生长的相关性。

Mol Cell Biochem. 1992 Jul 6;113(1):1-15. doi: 10.1007/BF00230880.

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