人源微小RNA hsa-miR-619-5p的血浆水平与前列腺癌超出包膜的扩散有关。
Plasma Level of hsa-miR-619-5p microRNA Is Associated with Prostatic Cancer Dissemination beyond the Capsule.
作者信息
Shkurnikov M Yu, Makarova Yu A, Knyazev E N, Fomicheva K A, Galatenko A V, Nyushko K M, Galatenko V V, Vechorko V I, Alekseev B Ya
机构信息
BioClinicum Research Centre, Moscow, Russia.
P. A. Herzen Moscow Oncology Research Institute, Affiliated Branch of National Medical Research Radiology Center, Ministry of Health of Russia, Moscow, Russia.
出版信息
Bull Exp Biol Med. 2017 Aug;163(4):475-477. doi: 10.1007/s10517-017-3831-x. Epub 2017 Aug 29.
Profiles of circulating microRNA in the plasma of patients with prostate cancer with pathomorphological stages pT2, pT3, and pT4 are analyzed. The level of circulating microRNA hsa-miR-619-5p is elevated in patients with extracapsular spreading of the tumor, increasing significantly from stage pT2 to stage pT4.
分析了前列腺癌患者处于病理形态学分期pT2、pT3和pT4时血浆中循环微RNA的特征。肿瘤包膜外扩散的患者中循环微RNA hsa-miR-619-5p水平升高，从pT2期到pT4期显著增加。
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