铜催化的硝基亚胺与二芳基碘鎓盐的 N-芳基化反应。
Copper-Catalyzed N-Arylation of Nitroenamines with Diaryliodonium Salts.
机构信息
Department of Chemistry, University of Veterinary Medicine , István utca 2, H-1078 Budapest, Hungary.
MTA-ELTE "Lendület" Catalysis and Organic Synthesis Research Group, Institute of Chemistry, Eötvös Loránd University , Pázmány Péter stny. 1/a H-1117 Budapest, Hungary.
出版信息
J Org Chem. 2017 Nov 17;82(22):11752-11764. doi: 10.1021/acs.joc.7b01591. Epub 2017 Sep 13.
A novel synthetic methodology was developed for the N-arylation of nitroenamine derivatives utilizing diaryliodonium triflates and copper(I) chloride as a catalyst. The procedure enables the easy aryl transfer from the hypervalent species under mild catalytic conditions with unusual heteroatom preference and high efficiency.
开发了一种利用二芳基碘鎓三氟甲磺酸酯和氯化亚铜作为催化剂的硝基亚胺衍生物的 N-芳基化的新型合成方法。该方法在温和的催化条件下，通过不寻常的杂原子偏好和高效率，使高价物种中的芳基很容易发生转移。
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