McClelland H A, Fairbairn A, McDonald M, Nicholas T R, Cox G A
Int Clin Psychopharmacol. 1987 Apr;2(2):159-64. doi: 10.1097/00004850-198704000-00010.
An ultrasound detector (UD) was compared with a clinical rating (CR) scale in the assessment of oro-facial movements in 23 chronic schizophrenic patients and 23 normal subjects over a period of 4 weeks. The apparatus distinguished well between normal volunteers and dyskinetic patients. There were also highly significant correlations between UD scores and clinical ratings. The results thus confirm both the construct and concurrent validity of the technique. Nevertheless, there was significant variation in the UD scores for some patients between assessments. A technical problem was the inability of some patients to cooperate for more than 30 seconds. The scores of the normal subjects were consistent. With further development and repeated 30-second assessments the technique might be of value in the ascertainment of early dyskinesia in patients at risk and also in measuring drug effects.
在为期4周的时间里,对23名慢性精神分裂症患者和23名正常受试者的口腔面部运动评估中,将超声探测器(UD)与临床评分(CR)量表进行了比较。该仪器能很好地区分正常志愿者和运动障碍患者。UD评分与临床评分之间也存在高度显著的相关性。因此,结果证实了该技术的结构效度和同时效度。然而,在评估期间,一些患者的UD评分存在显著差异。一个技术问题是一些患者无法配合超过30秒。正常受试者的评分是一致的。随着进一步的发展和重复的30秒评估,该技术可能在确定有风险患者的早期运动障碍以及测量药物效果方面具有价值。