Chakravarti Debabrata, Hazra Tapas K
Department of Obstetrics and Gynecology and Department of Pharmacology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA.
Cell Rep. 2017 Aug 29;20(9):1995-1996. doi: 10.1016/j.celrep.2017.08.045.
Nucleotide excision repair (NER) requires replication protein A (RPA), among others, to respond to DNA damaging agents. In this issue of Cell Reports, He et al. (2017) and Zhao et al. (2017) show acetylation of RPA1 regulates the UV-induced DNA damage response.
核苷酸切除修复（NER）除其他因素外，还需要复制蛋白A（RPA）来应对DNA损伤剂。在本期《细胞报告》中，何等人（2017年）和赵等人（2017年）表明，RPA1的乙酰化调节紫外线诱导的DNA损伤反应。
